Adverse Effects of Vaccines: Evidence and Causality
Institute of Medicine, Board on Population Health and Public Health Practice, Committee to Review Adverse Effects of Vaccines
National Academies Press, Apr 26, 2012 - Medical - 894 pages
In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children.
Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.
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3 Evaluating Biological Mechanisms of Adverse Events
4 Measles Mumps and Rubella Vaccine
5 Varicella Virus Vaccine
6 Influenza Vaccine
7 Hepatitis A Vaccine
12 InjectionRelated Adverse Events
13 Concluding Comments
List of Adverse Events
Literature Search Strategy
Causality Conclusion Tables