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abdominal abnormalities acetaminophen acid acidosis acute administration adults agents airway altitude Ann Emerg antibiotics anticholinergic arterial associated asthma bacteremia bacterial benzodiazepines blood cardiac cause chest child chronic Clin Toxicol Clinical Features cocaine common decreased Department of Emergency diagnosis Diagnostic Strategies digoxin dose drug dysrhythmias ectopic pregnancy edema effects electrical injury electrolyte Emergency Medicine emergency physician ethylene glycol evaluation exposure FACEP febrile fetal fever fluid fractures headache hepatic Hospital hypertension hypotension hypothermia hypoxia increased infants infection ingestion initial injury intoxication intravenous levels MDMA meningitis metabolic methanol mg/kg monitoring muscle neurologic normal occur onset opioid oral overdose oxygen pain patients Pediatr pneumonia poisoning pressure Principles of Disease pulmonary pulmonary edema radiograph renal require respiratory result rewarming rhabdomyolysis risk seizures serotonin syndrome serum severe signs sodium stridor symptomatic symptoms syndrome tachycardia temperature therapy tissue toxicity trauma treatment urinary urine usually vascular ventricular vomiting