Principles of Neural ScienceEric R. Kandel, James H. Schwartz, James Harris Schwartz "Four major advances have occurred since the appearance of the first edition of Principles of Neural Science, and they have stimulated us to undertake this revision earlier than we had planned. The first advance has been an application of recombinant DNA and monoclonal antibody techniques to the nervous system. These methods have made accessible the solution of many neurobiological problems;...The second important advance is patch clamping, which has allowed investigators to explore in intact membranes the conformational changes that occur in single ion channels...The third advance, the revolution in nerve cell labeling and cell tracing methods, has clarified many previously poorly understood relationships between brain structure and behavior. Fourth, new, noninvasive methods of imaging have made it possible to study anatomical structures in the living human brain. Because of these last two advances, neuroanatomy can now be taught in an integrated manner with other segments of neural science...The second edition is again designed as an introductory text for students of biology, behavior, and medicine. A major change in this edition is a more extensive treatment of neuroanatomy. The growth of functional neuroanatomy has made it possible both to describe the principles that underlie the anatomical structure of each system of the brain and to discuss each structure in terms of its physiology on the one hand, and its role in behavior and disease on the other. Our goal in this textbook is to convey the interest and excitement surrounding the application of cell- and molecular-biological techniques to the study of the nervous system, how the brain develops, and how it controls behavior. This text also emphasizes those neurological and behavioral disorders that are both instructive scientifically and important clinically... |
Contents
Nerve Cells Are the Signaling Units | 13 |
of Behavioral Responses | 19 |
Cognitive Function Can Be Localized | 25 |
Copyright | |
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Principles of Neural Science Eric R. Kandel,James H. Schwartz,James Harris Schwartz Snippet view - 1981 |
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action potential activity afferent fibers aphasia auditory axons basal ganglia behavior brain stem caudal caudate nucleus cell body central nervous system cerebellar cerebellum cerebral cortex channels Chapter chemical clinical cortical corticospinal corticospinal tract cranial nerves dendrites depolarization disease dorsal root electrical end-plate end-plate potential excitatory extracellular Figure function ganglion cells gyrus hair cells hemisphere hypothalamus inhibition inhibitory innervate input interneurons lateral geniculate nucleus layer lesions limb lobe mechanisms medial medulla membrane potential midbrain motor cortex motor neurons muscle fibers myasthenia myelin nerve cells neural normal organization parietal pathways patients peptides peripheral physiological pons posterior postsynaptic premotor presynaptic primary produced protein receptive field receptor reflex regions relay release response reticular retina signal sleep somatic sensory specific spinal cord stimulation structures synaptic potential temporal terminals thalamus tion tract transmitter trigeminal types ventricle vesicles vestibular visual cortex zone Δ Δ