Stem Cell Research Advances
Lydia P. Davenport
Nova Biomedical Books, 2007 - Medical - 286 pages
Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, autoimmune diseases as well as Parkinsons disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinsons disease, and Alzheimers disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This book presents leading-edge research in this rapidly-growing field.
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acute adult stem cells allogeneic angiogenesis antigen articular cartilage defects astrocytes autologous Bcr-Abl blood stem cell BMSC bone marrow stromal bone marrow transplantation brain busulfan cancer CD34+ cells cell depletion cell types chemotherapy chronic myelogenous leukemia chronic myeloid leukemia Clin clinical CML patients conditioning regimen coronary sinus culture cyclophosphamide cytokines dose drug effects embryonic stem cells expression function G-CSF gene genetic graft graft-versus-host disease growth factor GvHD Hematol hematologic hematopoietic stem cell HSCT human imatinib immune induced infection inhibition inhibitor injury lineage lymphoma malignancies markers marrow stromal cells melphalan mesenchymal stem cells mice molecular mouse MSCs multiple myeloma mutations myocardial nervous system neural differentiation neural stem cells neurological neurons Neurosci neurospheres NSCs Oncol potential progenitor cells proliferation receptor relapse responses retinal stem cells retinoblastoma self-renewal spinal cord stem cell transplantation stromal cells survival therapeutic therapy tissue toxicity treatment tumor vitro vivo