Safety of Silicone Breast Implants

Front Cover

The Dow Corning case raised serious questions about the safety of silicone breast implants and about larger issues of medical device testing and patient education.

Safety of Silicone Breast Implants presents a well-documented, thoughtful exploration of the safety of these devices, drawing conclusions from the available research base and suggesting further questions to be answered. This book also examines the sensitive issues surrounding women's decisions about implants. In reaching conclusions, the committee reviews:

  • The history of the silicone breast implant and the development of its chemistry.
  • The wide variety of U.S.-made implants and their regulation by the Food and Drug Administration.
  • Frequency and consequences of local complications from implants.
  • The evidence for and against links between implants and autoimmune disorders, connective tissue disease, neurological problems, silicone in breast milk, or a proposed new syndrome.
  • Evidence that implants may be associated with lower frequencies of breast cancer.

Safety of Silicone Breast Implants provides a comprehensive, well-organized review of the science behind one of the most significant medical controversies of our time.

 

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Contents

EXECUTIVE SUMMARY 1
INTRODUCTION 13
SILICONE CHEMISTRY 39
IMPLANT CATALOGUE 54
Implants from Dow Corning 69
Bioplasty and Other Manufacturers 76
5
6
9
WITH SILICONE BREAST IMPLANTS 242
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REFERENCE LISTS 285
xiii
APPENDIXES
B Description of the Public Meeting 488
Review of the Reports of the Independent Review

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10
8
Glossary 515
INDEX 525
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