Advances in Assisted Reproductive TechnologiesZ. BenRafael, Neri Laufer, Shlomo Mashiach, Joseph G. Schenker The World Congress of In Vitro Fertilization and Alternate Assisted Reproduction, held in Jerusalem, Israel, 2-7 April, 1989, was the sixth in the sequence of these Congresses, but was the first to emphasize the major importance and the place of assisted reproductive technologies in the treatment of infertility. The eternal City of Jerusalem witnessed the gathering of more than 1500 participants from allover the world who shared and exchanged knowledge and up-to-date experience in this ever-evolving field. The high quality scientific contributions to the Congress culminated in the publication of this Proceedings. It embraces all-important aspects in the field of in vitro fertilization and alternate assisted reproduction. Papers on controversies and diversities of methods to stimulate the ovaries, imaging techniques, basic research and state-of-the-art papers on ovarian physiology, the role of GnRH and its analog, clinical aspects of IVF treatment and cryopreservation, up-to-date techniques in assisted reproductive technologies that are quickly developing in conjunction with IVF, were included. When should IVF be preferable to surgery? What are the ex pected up-to-date world results and what are the psychological, moral, ethical and religious implications? These are all the concerns of the treating team and are addressed here. Male factor infertility remains a frustrating problem, but advances in the understanding of sperm-egg interaction, sperm evaluation and preparation are reported. Micromanipulation emerges as a possible alternative to bring some relief to this problem, but it also promises to be central in promoting the field of prenatal genetic analysis. |
Contents
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Physiology of Follicle Development in Stimulated Cycles | 47 |
Safe Gonadotropins | 53 |
Experience with GnRHAgonists in Ovarian Stimulation | 65 |
The Association of Ovarian Hyperstimulation and Zygote Intrafallopian | 77 |
Transvaginal Color Doppler in the Study of Uterine Perfusion | 541 |
Ultrasonographic Prediction of Ovarian Hyperstimulation OHS after IVF | 559 |
Ten Years Experience with Simplifications in IVF | 567 |
Comparison of Cryoprotectants and Stages of Human Embryo | 573 |
Ultrarapid Freezing | 589 |
World Results of Human Embryo Cryopreservation | 601 |
Influence of the Cooling Gradient and the Choice of Used Cryoprotectant | 611 |
Basic Concepts and Future Trends in Sperm Cryopreservation | 627 |
Control of Follicular Growth during the Primate Menstrual Cycle | 83 |
Growth Factor Modulation of Gonadotropin Action on Porcine Granulosa | 93 |
Activation of Collagenolysis | 103 |
Involvement of Calcium in the Transduction of the Hormonal Signal | 113 |
Hydration as the Key Event in Mucification of the Rat Cumulus | 119 |
Tumor Necrosis Factor TNFα and the Endogenous Prostaglandin Inhibitor | 129 |
The Role of Tumor Necrosis Factor in Human Granulosa Cells and Early | 139 |
vii | 145 |
The Ovarian ReninAngiotensin System and Compartmental Function in | 147 |
Prolactin as a Possible Modulator of Gonadotropin Action on the Ovary | 169 |
Studies on Pharmacokinetics of LHRH Analogues after Different Modes | 175 |
Pathophysiology | 195 |
GnRH Peptides and Corpus Luteum Regulation | 201 |
New Developments for Indications in Reproductive | 213 |
IVF versus GIFT | 221 |
Patient Selection for Assisted Procreation | 227 |
The Intratubal Transfer of Pronucleus and Early Embryonic Stage Embryos | 247 |
Tubal Embryo Transfer TET for the Treatment of Couples with Oligo | 255 |
Lessons Learned from IVC Intravaginal Culture | 267 |
The Benefits of Tubal Transfer Procedures | 271 |
Selection Criteria for Microsurgery GIFT and IVF | 287 |
Tubotubal Anastomosis versus In Vitro Fertilization in the Management | 297 |
Ectopic Pregnancy and the Decision to Undergo IVFET | 305 |
The Endocrinology of Stimulated Cycles and Influence on Outcome | 311 |
The Influence of Age Uterine Length Prepost Egg Retrieval Plasma | 327 |
The Timing of Embryo Transfer and Implantation | 335 |
Luteal Phase and Embryonic Development in GnRHAgonisthMGCycles | 351 |
Follicular Phase Gonadotropinreleasing Hormone Agonist and Human | 359 |
The Influence of Endometrial Preparation Protocols on Embryo Implantation | 373 |
Natural or Artificial Cycles? | 381 |
Improvement of Ovarian Response to Induction of Superovulation with | 389 |
The Permissive Role of Growth Hormone in Ovulation Induction with Human | 397 |
Synchronization of Donor and Recipient Cycles in an Egg Donation | 409 |
Carbohydratedmediated SpermEgg Interactions in Mammals | 437 |
The Role of IVF in Male Infertility | 453 |
Microsurgery Andrology and its Role in IVF | 465 |
New Possible Methods for Evaluation of Sperm Quality | 483 |
Ultramorphologic Characteristics of Human Sperm Cells | 493 |
Assessment of Human Spermatozoa Dysfunction and | 515 |
Introduction to the Technology of Magnetic Resonance Imaging | 525 |
Doppler Ultrasound in Infertility | 533 |
Oocyte Donation State of the Art 1989 | 633 |
Synchronization in Ovum Donation | 643 |
In Vitro FertilizationSurrogate Gestational Pregnancy | 649 |
Success Rate of Surrogate Gestational Pregnancies Using In Vitro | 657 |
Semen Donation and Sex Selection | 671 |
Recent Progress in Blastocyst Implantation Research | 677 |
Surrogates for the Blastocyst | 687 |
A Role for Platelet Activation Factor in Embryo Implantation | 697 |
The Requirement for Proteinase Cascade | 715 |
The Implantation Window in Humans after Fresh or Frozenthawed Embryo | 729 |
NonInvasive Biochemical Methods for Assessing Human Embryo Quality | 737 |
Pregnancy Rate and Pregnancy Outcome Associated with Laboratory Evaluation | 745 |
Assessment of Embryo Quality and Viability through Embryoderived Platelet | 767 |
Coculture of Human Zygotes on Fetal Bovine Reproductive Tract Cells | 779 |
Epithelial Cells from Human Fallopian Tube in Culture | 795 |
Cytoplasmic Control of the Transformation of Sperm Nucleus into Male | 807 |
Partial Zona Dissection for Enhancement of Sperm Passage through the Zona | 815 |
The Microinjection Technique and the Role of the Acrosome Reaction | 825 |
Microinsemination of Human Oocytes | 841 |
Sperm Injection into the Perivitelline Space of the Oocyte | 851 |
Results of In Vitro Fertilization of Human Oocytes after Zona Drilling | 861 |
Rapid Sexing of Preimplantation Mouse Embryos by Blastomere Biopsy | 871 |
Proliferation of Cells Derived from the Biopsy of Preimplantation Embryos | 887 |
Approaches and Current Status | 899 |
The Feasibility of PreimplantationEmbryo Biopsy and Genetic Screening | 903 |
Implication in Embryo | 919 |
Nuclear Transfer | 929 |
MMTVNras Transgenic Mice as a Model for Altered Capacitation Male | 939 |
The IVF Followup Clinic as a Tool | 959 |
A Phenomenological | 965 |
Perceived PsychoSocial Features of IVF Compared to Other Treatments | 973 |
PsychoSocial Profile of IVF Patients | 985 |
European IVF Results for 1987a Attempts and Pregnancy Outcome | 991 |
IVF Results in Eastern Europe | 1001 |
Pregnancy Rates and Perinatal Outcome in Australia and New Zealand | 1019 |
Survey of Assisted Reproductive Technologies in Asia and Africa Up to 31st | 1033 |
Ethical Religious and Legal Debate on IVF and Alternate Assisted | 1041 |
EDITORS PERSPECTIVE | 1053 |
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Advances in Assisted Reproductive Technologies Z. BenRafael,Neri Laufer,Shlomo Mashiach,Joseph G. Schenker No preview available - 2011 |
Common terms and phrases
acrosome reaction activity Advances in Assisted agonist analysis antibodies assay Assisted Reproductive Technologies Biol biopsy blastocyst blastomeres bryos buserelin calcium clinical concentrations couples cryopreservation culture cycle donor ectopic effect eggs embryo transfer Endocrinology epididymis estradiol fallopian follicles follicular fluid follicular phase freezing function gamete gene GnRH GnRH-a gonadotropin granulosa cells growth hamster hormone human embryos human oocytes implantation increase incubated induced infertility inhibition inhibitors injection insemination IVF/ET levels LH surge LHRH luteal phase luteinizing male factor Mashiach medium membrane microinjection morphological motility ng/ml normal ovarian stimulation ovary ovulation patients pituitary plasma Plenum Press pregnancy rate preimplantation preovulatory procedure progesterone prorenin prostaglandin protein protocol receptor renin Reprod role Sathananthan secretion semen serum sperm spermatozoa stage Steril Table technique thawing tion tissue treatment trophoblast Trounson tubal tube uterine vitro fertilization vivo zona pellucida zygotes