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acids activity adult air pollution alcohol animals areas arterial asbestos associated atherosclerosis Auth benzo(a)pyrene blood pressure Buerger's disease cadmium carbon monoxide carboxyhemoglobin carcinogens carcinoma cardiovascular CEA levels cessation cholesterol chronic bronchitis cigarette smoking cigarettes a day cigarettes per day clinical compared concentration consumption coronary heart disease death rates December l976 difference drug effects of smoking environmental epoxide etiology ex-smokers exposure female fractions heavy smokers higher hydrocarbons hypertension incidence increased induced inhaled kidney liver lung cancer lung cancer deaths male metabolism mortality myocardial infarction ng/ml nicotine nonsmokers number of cigarettes observed occupational October l976 passive smoking patients percent percentage plasma polycyclic population problem protein pulmonary ratio rats reduce Research respiratory risk factors serum cholesterol significantly silicosis Smoking and Health smoking habits stillbirth stop smoking subjects suggested survey thiocyanate tion tissue tobacco products tobacco smoke treatment tumor variables women