Cancer Chemotherapy |
Contents
PRIMARY SCREENING OF ANTITUMOUR COMPOUNDS | 3 |
METHODOLOGY OF PRIMARY SCREENING OF ANTITUMOUR Com | 28 |
ASPECTS OF WORK WITH ASCITES TUMOURS AND LEUKAEMIA | 40 |
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5-fluorouracil actinomycin action acute leukaemia administration alkylating agents Amethopterin animal tumours antibiotic antimetabolites antitumour activity antitumour drugs antitumour effect ascites azaserine blood bone marrow Burchenal Cancer Res carcinoma chemotherapy chlorambucil chloroethylamines chronic myeloid leukaemia clinical trials colchamine complete regression compounds course cure depression dopan Ehrlich tumour Endoxan example Experimental experiments folic acid given haemopoiesis haemopoietic system Hodgkin's disease human tumours inhibition of tumour injection intraperitoneal intravenously investigations Larionov leucocytes lung cancer lymphocytes lymphoid leukaemia lymphosarcoma Malignant Tumours mammary maximum tolerated dose mercaptopurine metastases method mg/kg mice Moscow Myleran N.Y. Acad nitrogen mustard Nitromin normal number of leucocytes observed obtained oestrogens onkol opukholei oral patients percentage inhibition preparations purine rat tumours remission resistant sarcolysin sarcoma 180 sarcoma 45 sensitivity shows side-effects strain substances substrain technique therapeutic effect thiophosphoramide thiotepa tissue total dose toxic effect transplantable tumours treatment tumour cells tumour growth Walker carcinosarcoma