Drug Design, Volume 10Everhardus Jacobus Ariëns |
Contents
Chapter | 2 |
Application of the Theory of Sets to Drug Design | 7 |
Drug Design in Practice | 17 |
Copyright | |
17 other sections not shown
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Common terms and phrases
acid active compounds activity profile analgesia analogs analysis antihypertensive atom benperidol bioactive agents Biol biological activity blood pressure butaclamol butyrophenone C₂ Calc calculated cardiac glycosides cardiac output cardiotonic CH₂ Chem clinical clozapine coefficients conformation copolymer correlation defined derived descriptors dexclamol discrimination drug action drug design drug-receptor interaction dynamics E. J. Ariëns effects elements Entomol enzyme excretion experimental factors H₂N haloperidol Hansch heparin hydrogel hypertensive implant kcal/mole lead compound lipophilicity matrix mechanisms medicinal objective membrane methods moiety molecular molecules mosquitoes multicollinearity multivariate neuroleptics nonempty intersection nonpeptidic opioids optimal parameters PBA systems PCILO peptides Pharmacol pharmacological physicochemical properties polymer polymeric potency potential Proc progesterone propranolol quantitative receptor regression release rate renin repellents ring set of compounds shows steric structural features structure-activity hypotheses structure-activity relationships subset substituents synthetic T₁ Table test compounds therapeutic therapy tissue total peripheral resistance toxicity variables vasodilator