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admission adolescence American Journal American Psychiatric Association antipsychotic medications Archives Birchwood BPRS Brief Psychiatric Rating British Journal clozapine cognitive cognitive therapy coping strategies depression diagnosis dose drug duration of untreated early detection early intervention early psychosis effective episode schizophrenia EPPIC factors Falloon first-episode psychosis first-episode schizophrenia follow-up functioning group programme hallucinations haloperidol high-risk hospital hospitalisation identified in-patient individuals initial Journal of Psychiatry markedly deviant behaviour McGorry mean s.d. measures ment Mental Disorders Mental Health months negative symptoms neuroleptic onset outcome PANSS participants patients period person phase phrenia positive symptoms premorbid prevention prodromal prolonged recovery Psychiatric Rating Scale psychological psychosocial psychotherapy psychotic disorders psychotic episode psychotic illness psychotic symptoms risk risperidone sample schizo schizoaffective disorder Schizophrenia Bulletin schizophreniform disorder scores self-efficacy showing markedly deviant social support stress substance misuse symp syndrome therapy tion University of Melbourne untreated psychosis variables