Targeted Therapies in Cancer:: Myth or Reality?

Front Cover
Francesco Colotta, Alberto Mantovani
Springer Science & Business Media, Dec 5, 2007 - Medical - 191 pages
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In September 2005 an International Meeting on "Targeted Therapies in Cancer: Myth or Reality" was held in Milan. This successful Meeting was intended to represent a forum for scientists and clinicians working in cancer drug discovery and therapy to share their reflections and experiences on how the paradigm shift from empiricism to molecular targeted therapies is contributing to the translation of basic knowledge into new therapies for cancer patients. This book collects the contributions given by scientists and clinicians, from Academia and Industry, who participated to this Meeting.

We hope that this book contributes to improve our approach to cancer drug discovery and, ultimately, to find new, more efficacious and better tolerated drugs for cancer patients. It provides an overview of diverse approaches ranging from drug discovery to cellular therapy. Although this change in paradigm has been useful, its entry into the clinical arena was associates with unforeseen problems including the emergence of resistance, unexpected side effects and failures. Time is therefore ripe for a critical cultural reflection on the state of the art, prospects and limitations. Ultimately, is targeted therapy in cancer a myth or a reality?

 

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Contents

colotta Ch_01pdf
1
colotta Ch_02pdf
5
colotta Ch_03pdf
19
colotta Ch_04pdf
43
colotta Ch_05pdf
54
colotta Ch_06pdf
74
colotta Ch_07pdf
88
colotta Ch_08pdf
100
colotta Ch_09pdf
112
colotta Ch_10pdf
128
colotta Ch_11pdf
144
colotta Ch_12pdf
155
colotta Ch_13pdf
177
colotta Indexpdf
187
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