Development of the Nervous System
Development of the Nervous System, Second Edition has been thoroughly revised and updated since the publication of the First Edition. It presents a broad outline of neural development principles as exemplified by key experiments and observations from past and recent times. The text is organized along a development pathway from the induction of the neural primordium to the emergence of behavior. It covers all the major topics including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, synapse formation and plasticity, and neuronal survival and death. This new text reflects the complete modernization of the field achieved through the use of model organisms and the intensive application of molecular and genetic approaches. The original, artist-rendered drawings from the First Edition have all been redone and colorized to so that the entire text is in full color. This new edition is an excellent textbook for undergraduate and graduate level students in courses such as Neuroscience, Medicine, Psychology, Biochemistry, Pharmacology, and Developmental Biology.
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Polarity and Segmentation
Genesis and Migration
Determination and Differentiation
Axon Growth and Guidance
Naturally Occurring Neuron Death
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AChR actin activity adhesion adult afferents Agrin animals auditory axons BDNF behavior binding Biol brain calcium cell death clusters cortical crest cells culture dendritic differentiation dorsal Drosophila ectoderm elimination embryo Ephrin-A5 expression fate fibers Figure filopodia floorplate function ganglia genes genetic glia glial glutamate granule cells growth cone hindbrain increase induced inhibition inhibitory innervation intracellular kinase labeled layer mechanisms membrane mesoderm mice microtubules migration molecular molecules motor neurons mouse muscle cells mutant nerve nervous system Netrin neural crest neural plate neural tissue neural tube neuroblasts neuron survival Neurosci neurotrophin NMDA normal Notch nucleus olfactory optic pathway pattern phosphorylation postnatal postsynaptic presynaptic progenitor cells proneural protein receptor region regulate retinal axons role sensory neurons signaling specific spinal cord stimulation studies subunit sympathetic neurons synapses target tectum telencephalon terminals tion transcription factors transplanted ventral vertebrate visual cortex vitro vivo Xenopus zone
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