PAHs and Related Compounds: Biology
Alasdair H. Neilson, O. Hutzinger
Springer Science & Business Media, Dec 17, 1997 - Medical - 386 pages
Environmental Chemistry is a relatively young science. Interest in this subject, however, is growing very rapidly and, although no agreement has been reached as yet about the exact content and limits of this interdisciplinary discipline, there appears to be increasing interest in seeing environmental topics which are based on chemistry embodied in this subject. One of the first objectives of Environ mental Chemistry must be the study of the environment and of natural chemical processes which occur in the environment. A major purpose of this series on Environmental Chemistry, therefore, is to present a reasonably uniform view of various aspects of the chemistry of the environment and chemical reactions occurring in the environment. The industrial activities of man have given a new dimension to Environ mental Chemistry. We have now synthesized and described over five million chemical compounds and chemical industry produces about hundred and fifty million tons of synthetic chemicals annually. We ship billions of tons of oil per year and through mining operations and other geophysical modifications, large quantities of inorganic and organic materials are released from their natural deposits. Cities and metropolitan areas of up to 15 million inhabitants produce large quantities of waste in relatively small and confined areas. Much of the chemical products and waste products of modern society are released into the environment either during production, storage, transport, use or ultimate disposal. These released materials participate in natural cycles and reactions and frequently lead to interference and disturbance of natural systems."
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Biotransformation of PAHs and Their Carcinogenic Effects in Fish
acid adducts formed anaerobic Anal Chem anthracene Appl Environ Microbiol Aquat Toxicol assessment bacteria Bacteriol benzene benzo[a]pyrene bioaccumulation bioavailability Biochem biological biotransformation biphenyl cancer carcinogen-DNA adducts carcinogenesis carcinogenic Cavalieri cells chemical concentrations contaminants cytochrome P450 degradation depurinating depurinating adducts detection dihydrodiol diol diol epoxide dioxygenase dioxygenation DMBA DNA adducts effects endpoints English sole Environ Contam Toxicol Environ Toxicol Chem environmental enzymes epoxide exposure fish fluoranthene fluorescence formation Gibson DT hepatic hydroxylation induced ionization ions Jankowiak laser lesions liver mechanism metabolism metabolites Microbial microsomes molecular monooxygenation mouse skin naphthalene neoplasms oligonucleotides one-electron oxidation organisms oxygen PAH-DNA adducts PAHs pathways phenanthrene pollution polycyclic aromatic hydrocarbons produced Pseudomonas putida pyrene radical cation rainbow trout reactions ring fission Rogan EG sediment Small GJ species spectra spectrum strain structure studies substrate tandem mass spectrometry TEFs tion toluene toxicity transformation tumor initiation uptake vitro vivo
Page v - Mackay Department of Chemical Engineering and Applied Chemistry University of Toronto Toronto, Ontario, Canada M5S 1A4 Prof.Dr.AHNeilson Swedish Environmental Research Institute PO Box 21060 10031 Stockholm, Sweden firstname.lastname@example.org Prof. Dr. J. Paasivirta Department of Chemistry University of Jyvaskyla Survontie 9 PO Box 35 40351 Jyvaskyla, Finland Prof.
Page ix - ... a privilege to see my chosen subject grow. My interest in Environmental Chemistry dates back to my early college days in Vienna. I received significant impulses during my postdoctoral period at the University of California and my interest slowly developed during my time with the National Research Council of Canada, before I could devote my full time of Environmental Chemistry, here in Amsterdam. I hope this Handbook may help deepen the interest of other scientists in this subject. Amsterdam,...
Page viii - Publisher and editor hope to keep materials of the volumes one to three up to date and to extend coverage in the subject areas by publishing further parts in the future. Plans also exist for volumes dealing with different subject matter such as analysis, chemical technology and toxicology, and readers are encouraged to offer suggestions and advice as to future editions of “The Handbook of Environmental Chemistry”.
Page ix - ... topics could not be fitted easily into the headings of the first three volumes. All five volume series are integrated through the choice of topics and by a system of cross referencing. The outline of the Handbook is thus as follows: 1. The Natural Environment and the Biochemical Cycles, 2. Reaction and Processes, 3. Anthropogenic Compounds, 4. Air Pollution, 5. Water Pollution. Rapid developments in Environmental Chemistry and the increasing breadth of the subject matter covered made it necessary...
Page ix - Hutzinger Twentyone years have now passed since the appearance of the first volumes of the Handbook. Although the basic concept has remained the same changes and adjustments were necessary. Some years ago publishers and editors agreed to expand the Handbook by two new open-end volume series: Air Pollution and Water Pollution. These broad topics could not be fitted easily into the headings of the first three volumes. All five volume series are integrated through the choice of topics and by a system...
Page ix - ... remained the same changes and adjustments were necessary. Some years ago publishers and editors agreed to expand the Handbook by two new open-end volume series: Air Pollution and Water Pollution. These broad topics could not be fitted easily into the headings of the first three volumes. All five volume series are integrated through the choice of topics and by a system of cross referencing. The outline of the Handbook is thus as follows: 1. The Natural Environment and the Biochemical Cycles, 2....