Chromosome Mutation and Neoplasia |
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Page 98
... clinical en- tities . The neoplasms that emerge in such persons are of a specific type and affect the particular tissue affected in the syndrome . Consequently , a specific neoplasm is often thought of as an integral part of the clinical ...
... clinical en- tities . The neoplasms that emerge in such persons are of a specific type and affect the particular tissue affected in the syndrome . Consequently , a specific neoplasm is often thought of as an integral part of the clinical ...
Page 146
... clinical effect on immune function- might be expected of the preferential overgrowth of a single lineage of T lymphocytes , but , if there is one , it has not been discovered . What effect might this have ? One of the major clinical ...
... clinical effect on immune function- might be expected of the preferential overgrowth of a single lineage of T lymphocytes , but , if there is one , it has not been discovered . What effect might this have ? One of the major clinical ...
Page 419
... clinical picture of the blast crisis . Similar sequential patterns of the karyotypic alteration associated with clinical progression have been reported in other human leukemic and preleukemic disorders [ 39,50 ] , but many cases do not ...
... clinical picture of the blast crisis . Similar sequential patterns of the karyotypic alteration associated with clinical progression have been reported in other human leukemic and preleukemic disorders [ 39,50 ] , but many cases do not ...
Contents
Blooms Syndrome | 7 |
Search for a Central Hypothesis | 23 |
Description of 26 | 43 |
Copyright | |
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aberrations abnormalities Acad activity acute agents alterations appear associated ataxia ataxia-telangiectasia blood Bloom's syndrome breakage breaks cancer carcinogens carcinoma cells cellular changes characteristic chemical chromosome clinical clones common cultures cytogenetic damage defect deficiency described disease disorders DNA repair DNA synthesis effect evidence families Fanconi's anemia fibroblasts frequency gene Genet genome GERMAN growth human incidence increased indicate individuals induced instability involved known lesions leukemia levels light lines lymphocytes malignant marrow mechanisms mutagens mutation Nature neoplasia neoplasms normal observed occur origin patients persons population possible present Press Proc produced radiation rearrangements recent repair replication reported response result sensitivity sister chromatid exchanges skin specific strains studies suggested Table telangiectasia tion tissue transformation translocation tumors types usually virus vitro Werner's xeroderma pigmentosum York