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Structure and Biosynthesis of Nerve Growth Factor
Structure and Biosynthesis
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Acad Sci USA aFGF amino acid antibodies astrocytes axons basal forebrain basic fibroblast growth bFGF binding Biochem Biol Chem biological activity Bothwell Brain Res c-fos C-kinase C-terminal cDNA Cell Biol cell line cell types cholinergic cholinergic neurons cloning complex culture differentiation effects enzymes fibroblast growth factor fimbria/fornix ganglia gene expression growth cone growth factor receptor Guroff Halegoua heparin high molecular weight hippocampal increased induced inhibit intracellular kallikrein kinase activity lesions levels Mastomys Mastomys NGF molecules mRNA Natl Acad Sci nerve growth factor nervous system neural neurite neurite growth neurite outgrowth Neurosci NGF action NGF mRNA NGF receptor NGF stimulated NGF treatment NGF-induced NGFR oncogene pathways PC 12 cells pheochromocytoma phosphorylation Proc Natl Acad protein kinase receptor gene regulation response to NGF role Schwann cells second messenger sequence Shooter specific studies submaxillary gland subunit suggested sympathetic synthesis Thoenen H tissues transcription transfected tumor vitro vivo