Virally Infected Cells
Cellular virology has made tremendous advances in the past decade due to the availability and application of new immunological techniques together with the vast range of biochemical techniques and the continued impact of transmission electron microscopy. The chapters contained in this volume provide significant coverage of the subject of cellular virology as a whole. Considerable overall emphasis is placed upon the membrane biochemistry of viral proteins and glycoproteins within the infected cell. In the opening chapter Edouard Kurstak and his colleagues provide a useful survey on the detection of viral antigens and antibodies by immunoassays. This chapter, with its emphasis on the important role of immunology in present-day virology, sets the scene for the volume. Following this is an exciting presentation from Stefan Hoglund and his colleagues on ISCOMs and immunostimulation with viral antigens. This unique approach is already proving to be of value, particularly in animal virology. A somewhat pharmacological diversion appears in Chapter 3, by Kazukiyo Onodera and his colleagues, in which the biological activity of the damavaricin C derivatives is discussed. This chapter provides a link between the biochemical and the chemotherapeutic approach in cellular virology. Yet another specialist area is covered in Chapter 4 by Otto Schmidt and hnke Schuchmann-Feddersen, who discuss the role of virus-like particles in para site-host interactions of insects. Contributing a strong biomedical emphasis to the volume is the provocative chapter by Abraham Karpas on human leukemia and retroviruses.
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Acad activity Albrecht amino acid antigen ATLV Biochem BTV-infected cells Cell Biol cell surface cells infected cellular DNA synthesis Chem CMV DNA synthesis CMV infection containing cytomegalovirus cytoplasmic cytoskeleton damavaricin detected DNA synthesis ELISA envelope enzyme etal flavivirus function fusion G protein gene genome glycoproteins glycosylation Golgi complex Helenius hemagglutinin host cell HTLV human cytomegalovirus immune induced infected cells influenza virus inhibition intracellular ISCOM isolated leukemia virus leukemic lipid mammalian membrane proteins molecular molecules monoclonal antibodies Morein mutants n-pentyl DvFc Natl Nature Land nucleocapsid oligosaccharides parasitoid patients peptides plasma membrane polymerase polypeptides Proc Quil receptor replication residues response retrovirus rubella virus Saccharomyces cerevisiae secretory serum Shida signal sequence specific spheroplasts strain streptovaricin structural proteins studies T-cell leukemia tion trans-type translocation transport vaccine vesicles vesicular viral proteins virions Virol Virology virus particles virus-like particles viruses vitro Westaway yeast