Goodman & Gilman's The Pharmacological Basis of Therapeutics, Eleventh EditionThe undisputed leader in medical pharmacology, without equal. Updated to reflect all critical new developments in drug action and drug-disease interaction. This is the “desert island” book of all medical pharmacology—if you can own just one pharmacology book, this is it. |
Contents
General Principles | 1 |
Drugs Acting at Synaptic and Neuroeffector Junctional Sites | 137 |
Drugs Acting on the Central Nervous System | 317 |
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5-HT receptors absorption action activity acute administration adrenergic receptors agents agonists anesthesia anesthetic antidepressants antipsychotic drugs atropine Baldessarini barbiturates benzodiazepines binding block blockade blood pressure brain Ca2+ carbamazepine cardiac cardiovascular catecholamines cells channels Chapter cholinergic Clin clinical clozapine compounds concentrations CYPs decrease depolarization depression disease disorders dopamine dosage doses efficacy enzymes epinephrine excreted function GABA GABAA receptor ganglia gene genetic half-life halothane heart hepatic human hypertension hypotension increase induced inhalational inhibition inhibitors interactions intravenous isoflurane liver local anesthetics mechanisms mediated membrane metabolism metabolites molecular muscarinic receptors nerve nervous system neurons neurotransmitter nicotinic norepinephrine occur oral oxide oxygen patients peripheral pharmacokinetic Pharmacol pharmacological phenytoin plasma polymorphisms potential produce propofol protein Psychiatry receptor antagonists release renal response result seizures selective serotonin side effects smooth muscle spinal stimulation structure substrate subtypes subunits sympathetic synaptic syndrome therapeutic therapy tion tissue toxicity transmitter transporters treatment