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acid activity acute animals assay assessment bioaccumulation Biol blood brain cadmium Canada carcinogenesis carcinogenicity cells Cent Chem chemical chlorinated CHLORINATED DIOXINS chronic ciguatera cocaine Coll compounds concentrations contamination cytochrome cytochrome P450 decreased detected Dioxins Dioxins and Related dose drug En;en environmental enzyme ethanol evaluated excretion exposed ﬁbers ﬁrst ﬁsh groups Health hepatic hepatocytes Hosp human increased induced inhalation inhibition inst irradiation ISSN Japan kidney levels lipid liver lung cancer male mercury metabolism metabolites metals mg/kg mice mutagenicity MUTAT Mycotoxins Natl occupational exposure oxide P.O. Box patients PCBs PCDFs pesticides plasma poisoning pollution protein radon rats receptors residues risk Salmonella samples serum signiﬁcant signiﬁcantly smoke speciﬁc Symposium on Chlorinated TCDD Thorotrast tion tissue toxicity toxicity testing TOXICOL toxin treatment tumors Univ Unlv uptake urinary urine venom vitro vivo