The Measurement of Linkage in HeredityTwo class segregations. The planning of experiments. The detection of linkage. The estimation of linkage. Information and the planning of experiments. Combined estimation and testing hererogeneity. Disturbed segregations. Human genetic (I), (II). The estimation of gene frequences. |
Contents
INTRODUCTORY | 1 |
TWO CLASS SEGREGATIONS | 13 |
INFORMATION AND THE PLANNING OF | 56 |
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a₁ a₂ AaBb AaBbCc x aabbCC AB/ab achromatopsia allelomorphs amount of information cent chapter column considered corresponding coupling and repulsion cross degrees of freedom detection of linkage dominant dominant genes efficient equation of estimation estimation of linkage example expected value F₂ Fisher four classes function gametes genetical genotypes give given groups hetero heterogeneity x2 heterozygote heterozygous homozygous human data hypothesis incomplete dominance linkage value m₁ m₂ Mather mating maximum likelihood method of maximum mum likelihood normal number observed number of individuals obtained orthogonal orthogonal functions P₁ parameter phenotypically probability progeny quantity R. A. Fisher recombination fraction retinitis pigmentosa scores sets of data sex linkage shown in Table sibs Sibship single backcross single factor ratios single factor segregations standard error statistic test of significance tion trial values type of family variance α₁