Handbook of Schizophrenia Spectrum Disorders, Volume I: Conceptual Issues and Neurobiological Advances
Michael S Ritsner
Springer Science & Business Media, Apr 6, 2011 - Medical - 494 pages
A few disorders have some of the same symptoms as schizophrenia including schizoaffective disorders, schizophreniform disorder, schizotypal and schizoid personality disorders, delusional disorder, and autism (schizophrenia spectrum disorders). Since the 2000 there has been significant progress in our understanding of the early presentations, assessment, suspected neuropathology, and treatment of these disorders. Recent technological breakthroughs in basic sciences hold promise for advancing our understanding of the pathophysiology of schizophrenia spectrum disorders. This collective monograph reviewers recent researches regarding the origins, onset, course, and outcome of schizophrenia spectrum disorders. In particular, this book will be illustrate new developments in terms of conceptual models, and research methodology, genetics and genomics, brain imaging and neurochemical studies, neurophysiology and information processing in schizophrenia spectrum disorders patients. Also will be highlighted new developments in our understanding of the childhood psychosis, prodromal and first-episode states, in treatment and rehabilitation. Thus, the purpose of this book is to provide up-to-date overview of the rapid advances made in the clinical and basic science studies supporting our understanding of the relationship between cerebral processes and clinical, cognitive and other presentations of the schizophrenia spectrum disorders. In addition, this book aims to monitor important research developments, which may be relevant to treatment, and rehabilitation of patients.
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2 Diagnosis and Classification of the Schizophrenia Spectrum Disorders
3 Toward a Multidimensional Continuum Model of Functional Psychoses for Research Purposes
4 Irving Gottesman and the Schizophrenia Spectrum
Reflections on the Bridge to Schizophrenia and Obstacles on the Road Ahead to Etiology and Pathogenesis
6 Autistic Spectrum Disorders and Schizophrenia
Genomic Psychological and Evolutionary Models of Autism in Relation to Schizophrenia
8 Quantifying the Dynamics of Central Systemic Degeneration in Schizophrenia
A Model for Biomarker Discovery in Schizophrenia
16 What Does Proteomics Tell Us About Schizophrenia?
Findings in Rodents Models and Clinical Populations
18 Neural Substrates of Emotion Dysfunctions in Patients with Schizophrenia Spectrum Disorders
A Review of the Evidence
20 Mapping Prodromal Psychosis
Contents to Volume II
9 Schizophrenia Has a High Heritability but Where Are the Genes?
10 Changes in Gene Expression in Subjects with Schizophrenia Associated with Disease Progression
11 Amino Acids in Schizophrenia Glycine Serine and Arginine
12 Developmental Consequences of Prenatal Exposure to Maternal Immune Activation
13 Glutamatergic Neurotransmission Abnormalities and Schizophrenia
14 Mathematical Models in Schizophrenia
Other editions - View all
abnormalities altered amygdala analysis antipsychotic Arch Gen Psychiatry assessment associated autism spectrum behavior Biol Psychiatry biomarkers bipolar disorder Brain Res changes cingulate Clin clinical cognitive controls criteria decreased deficits depression developmental diagnostic dimensional disease dopamine dopaminergic DSM-IV dysfunction dysregulation effects emotion endophenotypes episode evidence factors first-episode schizophrenia fMRI frontal functional psychoses genetic genome glutamate Gottesman grey matter gyrus hippocampus imaging impairment increased interactions ketamine levels mediated meta-analysis methamphetamine negative symptoms neural neurocognitive neurodevelopmental neuroimaging neurons Neurosci NMDA receptor NMDAR offspring onset PANSS patients with schizophrenia phenotypes prefrontal cortex prenatal immune activation prodromal protein proteome Psychiatry psychopathology psychosis psychotic disorders psychotic symptoms rats regions response Ritsner schizoaffective disorder Schizophr Bull Schizophr Res schizophrenia schizophrenia and bipolar schizophrenia patients schizophrenia spectrum disorders schizotypal personality disorder social Springer Science+Business Media stress structure studies subjects with schizophrenia syndrome temporal tion treatment