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abnormal acetate and lead acute affected alcoholic myopathy appearance aqueous uranyl acetate Arch arteries atrophied muscle fibres axons cause central core disease chloroquine Chloroquine myopathy chronic clinical condition connective tissue creatine described diagnosis disorders Dubowitz dystrophia myotonica Electromyography Electron micrograph electron microscope enzyme excised fibrous Figure glycogen Haematoxylin Haematoxylin and eosin histochemical histological human muscle inflammatory innervation intramuscular J. N. Walton lead citrate lesion limb muscles longitudinal section lysosomes McArdle's membrane metabolic mitochondria motor neurone disease motor unit muscle biopsy muscle cell muscle diseases muscle dystrophy muscle fibres muscle fibres show muscle spindles muscle weakness muscular dystrophy myasthenia gravis myofibrils myofilaments myositis necrosis nemaline nerve trunks neuropathy occur paralysis Pathology patient Pearson Photomicrograph polyarteritis nodosa polymyositis present reaction rheumatoid arthritis sarcoidosis sarcolemmal nuclei sarcoplasm seen serum enzyme skeletal muscle stage steroid striated muscle studies syndrome tion transverse section trauma tumours usually Voluntary Muscle Werdnig-Hoffmann disease