Nanobiotechnology: Concepts, Applications and Perspectives, Volume 1

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Christof M. Niemeyer, Chad A. Mirkin
John Wiley & Sons, Mar 12, 2004 - Science - 469 pages
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Nanotechnology is the key technology of the 21st century. The possibility to exploit the structures and processes of biomolecules for novel functional materials, biosensors, bioelectronics and medical applications has created the rapidly growing field of nanobiotechnology.
Designed as a broad survey of the field, this book combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science and bioanalytics to fathom the full scope of current and future developments.
It is divided into four main sections:
* Interphase Systems
* Protein-based Nanostructures
* DNA-based Nanostructures
* Nanoanalytics
Each chapter describes in detail currently available methods and contains numerous references to the primary literature, making this the perfect "field guide" for chemists, biologists and materials scientists who want to explore the fascinating world of nanobiotechnology.
 

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Contents

Thomas Sawitowski
1
Microcontact Printing of Proteins
31
CellNanostructure Interactions
53
Powell Markus Seitz
54
Defined Networks of Neuronal Cells in Vitro
66
USA SAS Nagar Sector
67
Proteinbased N a restructures
77
Murali Sastry and Ludwig Boltzmann Institute
90
Cell Biology and Genetics
189
Nanoparticle Biornaterial Hybrid Systems
200
DNAbased Nanostructures
227
DNAtemplated Electronics
244
Biomimetic Fabrication of DNAbased Metallic Nanowires and Networks
256
DNAColdNanoparticle Conjugates
288
Nanoparticles as NonViral Transfection Agents
319
Nanoanalytics
343

Engineered Nanopores
93
Bernhard Schuster Germany
108
Cenetic Approaches to Programmed Assembly
113
Microbial Nanoparticle Production
126
Nanoscale Magnetic Iron Minerals in Bacteria
136
Bacteriorhodopsin and its Potential in Technical Applications
146
Polymer Nanocontainers
168
Biomolecular Motors Operating in Engineered Environments
185
Nanoparticle Molecular Labels
353
Analysis of Biomolecular Structure
387
Force Spectroscopy
404
Biofunctionalized Nanoparticles for SurfaceEnhanced
429
Bioconjugated Silica Nanoparticles for Bioanalytical Applications
444
Index
458
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About the author (2004)

Christof M. Niemeyer is Professor of Chemistry at the University of Dortmund (Germany) where he holds the chair of Biological and Chemical Microstructuring. He was born in Cloppenburg and studied chemistry at the University of Marburg. He did his thesis at the Max-Planck-Institut f1⁄2r Kohlenforschung in M1⁄2lheim/Ruhr under the supervision of Manfred T. Reetz and his postdoctorate with Charles R. Cantor at the Center for Advanced Biotechnology in Boston (USA). He then went back to Germany, where he worked with Dietmar Blohm at the University of Bremen to complete his habilitation before moving to Dortmund as a full Professor in 2002. He is interested in semisynthetic DNA-protein and -nanoparticle conjugates and their applications in life-sciences, catalysis and molecular nanotechnology.
******
Chad A. Mirkin is the George B. Rathmann Professor of Chemistry and the Director of the Institute for Nanotechnology and the Center for Nanofabrication and Molecular Self-Assembly at Northwestern University in Evanston.
Professor Mirkin holds a B.S. degree from Dickinson College (1986) and a Ph.D. degree in chemistry from The Pennsylvania State University (1989). He was a NSF Postdoctoral Fellow at the Massachusetts Institute of Technology before becoming a chemistry professor at Northwestern University in 1991.
Professor Mirkin is known for his development of nanoparticle-based biodetection schemes and his invention of Dip-Pen Nanolithography. He is the founder of two companies, Nanosphere and NanoInk, which are commercializing nanotechnology applications in the life science and semiconductor industries.
Professor Mirkin has been recognized for his accomplishments with the 2004 Nobel Laureate Signature Award for Graduate Education in Chemistry (2003), the 2003 Raymond and Beverly Sackler Prize in the Physical Sciences, the 2002 Feynman Prize in Nanotechnology, the 2001 Leo Hendrick Baekeland Award, the Discover 2000 Award for Technological Innovation, I-Street Magazine's Top 5 List for Leading Academics in Technology, the Materials Research Society Young Investigator Award (2000), the ACS Award in Pure Chemistry (1999), the PLU Fresenius Award (1998), the Harvard University E. Bright Wilson Prize (1998), and the BF Goodrich Collegiate Inventors Award (1997).

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