NIH: An Account of Research in Its Laboratories and Clinics

Front Cover
DeWitt Stetten
Academic Press, May 10, 2014 - Medical - 572 pages
NIH: An Account of Research in Its Laboratories and Clinics contains collected accounts of the Intramural Research Program, as they happened in the laboratories and clinics, in various installations of the National Institutes of Health across the U.S.A. One paper discusses the etiology of schizophrenia which notes that, based on evidence and expanded adoption studies by Ketty, Rosenthal, and Wender, genetic factors actually contribute to the development of the disease. In developing countries, schizophrenia follows a more benign course. Some papers describe bacteriology, mycology, viral hepatitis, basic immunology, clinical immunology, and the development of enzymology. Researchers studying proteins elucidate on the synthesis and folding of protein chains, protein conformation and dynamics, the semisynthesis and protein function, as well as on sequence analysis and collagen research. Other papers describe the breaking of the genetic code, the progress made from the genetic code to beta thalassemia, to investigations of genetic diseases (such as galactosemia, gout, Lesch-Nyhan disease, mucopolysaccharide storage disease, and sickle cell disease). One paper notes the contribution of the intramural clinical research program of the National Cancer Institute to cancer therapy with emphasis in cancer chemotherapy. Professors in pharmacology, practitioners of general medicine, specialists or researchers dealing with microchemistry, toxicology, drug therapy, or oncology will find the collection valuable.
 

Contents

CHAPTER 1 PROLOGUE
1
CHAPTER 2 THE EARLY DAYS
6
CHAPTER 3 STUDIES ON THE ETIOLOGY OF SCHIZOPHRENIA
13
CHAPTER 4 NEUROTRANSMITTERS AND NEUROPSYCHOPHARMACOLOGY
36
CHAPTER 5 THE NEUROSCIENCESBASIC AND CLINICAL
48
CHAPTER 6 NUTRITION RESEARCH
72
CHAPTER 7 TISSUE CULTURE
88
CHAPTER 8 BACTERIOLOGY AND MYCOLOGY
114
CHAPTER 15 FROM THE GENETIC CODE TO BETA THALASSEMIA
298
CHAPTER 16 GENETIC DISEASES
307
CHAPTER 17 VIRAL ONCOLOGY
350
CHAPTER 18 VIROGENES TO ONCOGENES
369
CHAPTER 19 SV40
380
CHAPTER 20 STUDIES ON SLOW VIRUS DISEASES
396
CHAPTER 21 ENDOCRINOLOGY
417
CHAPTER 22 SPECTROSCOPY AND CHEMICAL PHYSICS
445

CHAPTER 9 VIRAL HEPATITIS
142
CHAPTER 10 IMMUNOLOGYBASIC AND CLINICAL
156
CHAPTER 11 ORGANIC CHEMISTRY IN A BIOMEDICAL RESEARCH ORGANIZATION
194
CHAPTER 12 DEVELOPMENT OF ENZYMOLOGY
222
CHAPTER 13 STUDIES ON PROTEINS
259
CHAPTER 14 A REVISIONIST VIEW OF THE BREAKING OF THE GENETIC CODE
282
CHAPTER 23 COMPUTERS IN BIOMEDICAL RESEARCH
457
CHAPTER 24 CARDIAC SURGERY
483
CHAPTER 25 THERAPEUTIC RESEARCH IN THE NATIONAL CANCER INSTITUTE
500
CHAPTER 26 EPILOGUE
527
INDEX OF NAMES
535
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