Epigenetic Inheritance and Evolution: The Lamarckian Dimension
Does the inheritance of acquired characteristics play a significant role in evolution? In this book, Eva Jablonka and Marion J. Lamb attempt to answer that question with an original, provocative exploration of the nature and origin of hereditary variations. Starting with a historical account of Lamarck's ideas and the reasons they have fallen in disrepute, the authors go on to challenge the prevailing assumption that all heritable variation is random and the result of variation in DNA base sequences. They also detail recent breakthroughs in our understanding of the molecular mechanisms underlying inheritance--including several pathways not envisioned by classical population genetics--and argue that these advances need to be more fully incorporated into mainstream evolutionary theory. Throughout, the book offers a new look at the evidence for and against the hereditability of environmentally induced changes, and addresses timely questions about the importance of non-Mendelian inheritance. A glossary and extensive list of references round out the book. Urging a reconsideration of the present DNA-centric view prevalent in the field, Epigentic Inheritance and Evolution will make fascinating and important reading for students and researchers in evolution, genetics, ecology, molecular biology, developmental biology, and the history and philosophy of science.
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inheritance of acquired characters
Induced genetic variations
The inheritance of directed
Interactions between genetic
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acquired characters active adaptive alleles altered associated bands become believed biology carry cause cells changes Chapter chromatin chromosomes complex culture cytoplasm depends determination developmental directed discussed DNA sequence early effects EISs elements environment environmental epigenetic epigenetic inheritance epigenetic variations evidence evolution evolutionary example experiments explanation expression factors female frequency functional gene genetic genome germ cells germ line groups heredity heritable heterochromatin hybrids ideas important imprinting inactive increase individuals induced influence inheritance inheritance of acquired inheritance systems involved known Lamarckian lead lineages locus male marks mechanisms memory methylation modified molecular multicellular mutations natural normal occur organisms origin parental particular patterns phenotype plants population possible present probably processes produce proteins random regions repeats replication reproduction response result role segregation selection similar somatic speciation species stage structure studies suggested theory tion transmission transmitted usually Weismann
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