Gene Therapy: Prospective Technology assessment in its societal context
Jörg Niewöhner, Christof Tannert
Elsevier, Aug 19, 2011 - Technology & Engineering - 274 pages
This book presents work that has been conducted as part of the research project "Discourse on ethical questions of biomedicine" of the interdisciplinary Working Group Bioethics and Science Communication at the Max-Delbrueck-Center for Molecular Medicine (MDC)in Berlin-Buch, Germany. This book offers ground-breaking ideas on how the daily interworking of cutting-edge biomedical research assess the broader social context and its communication to stakeholders and the public. Editors cover three aspects: Scientific, Ethical and Legal, and Perception and Communication. This work establishes an international and interdisciplinary network of excellent researchers at the beginning of their careers, who brilliantly integrate their work into the different perspectives on gene therapy from the natural and social sciences, as well as the humanities and law.
* Discusses biological and cellular barriers limiting the clinical application of nonviral gene delivery
* Addresses such questions as: Does patent granting hinder the development of Gene Therapy products?
* Offers insight in the future of public perception of gene therapy in Europe
* Provides details on how to communicate risks in gene therapy
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Acad adeno-associated virus adeno-associated virus vectors adenovirus applications approach bioethics biotechnology brain BRCA1 BRCA2 breast and ovarian breast cancer Chem China clinical trials context cultural decision diagnostic discussion disease disorders Drug efficient embryo endosomal enhancement Eugenics fetal gene therapy FMRI Gendicine gene carriers gene delivery gene expression Gene Ther gene therapy research gene transfer genetic testing germ-cell gene therapy germline heart heteroplex human genome individuals injection interventions issues laypersons medicine molecular moral mutations Myriad Genetics Natl non-viral gene delivery October 17 ovarian cancer patent perfusion polymeric polymers polyplexes potential proteins protocol rAAV rAAV2 recombinant adeno-associated regarding regulation reproductive autonomy retinitis pigmentosa risk assessment risk communication risk perception role scientific scientists sequence serotypes social society somatic cell gene specific targeting therapeutic tion transduction transfection transgene treatment uncertainty verbal viral vectors virtue ethics visited October 17 vivo