Cancer Drug Discovery: Science and HistoryThe reader will discover a comprehensive and multifaceted overview of the history of the development of anticancer drugs deeply influenced by the cell concept of cancer and future directions for the development of new anticancer drugs. First, this book documents the scientific progress in biological science over the last 70 years and the influence this progress had in cancer research. Summaries and charts of important discoveries complete this overview. Furthermore, this book outlines the process of anticancer drug development with a focus on the characteristic drug groups of each era, related to advancements of chemistry and biological sciences. This book also provides brief mechanism of action of drugs, illustrated by comprehensive timelines and conceptual cartoons. This book finally sums up the limitations of the current anticancer drug development and seeks new directions for anticancer drug discovery, considering under the systemic view of cancer. |
Other editions - View all
Cancer Drug Discovery: Science and History Kyu-Won Kim,Jae Kyung Roh,Hee-Jun Wee,Chan Kim No preview available - 2016 |
Cancer Drug Discovery: Science and History Kyu-Won Kim,Jae Kyung Roh,Hee-Jun Wee,Chan Kim No preview available - 2018 |
Common terms and phrases
acid activity acute alkaloids alkylating androgen angiogenesis antibiotics anticancer agents anticancer drugs anticancer effect antitumor apoptosis aromatase asparaginase Bcr-Abl binding bleomycin breast cancer cancer cells Cancer Drug cancer patients Cancer Res cancer research cancer treatment carcinoma caused cell division cell network Chem chemotherapy chromosome chronic cisplatin clinical trials combination chemotherapy compounds cytokines cytotoxic derivatives developed discovered Discovery doxorubicin efficacy EGFR endothelial cells enzymes erlotinib estrogen FDA approved function gefitinib gene genetic HDAC HER2 histone hormone human imatinib induced inhibits leukemia LHRH lung cancer lymphocytic lymphoma malignant Mechanism of action melanoma metastasis mice monoclonal antibody mouse mutations Natl Acad Sci nitrogen mustard observed oncogene paclitaxel pathway Pemetrexed phase Proc Natl Acad prostate cancer protein sarcoma sorafenib studies suppressed synthesis tamoxifen targeted anticancer thalidomide therapeutic agent therapeutic effect therapy tissue topoisomerase toxicity transplantation trastuzumab treat tumor tumor cells types tyrosine kinase various VEGF xenograft
Bibliographic information
| Title | Cancer Drug Discovery: Science and History |
| Authors | Kyu-Won Kim, Jae Kyung Roh, Hee-Jun Wee, Chan Kim |
| Edition | illustrated |
| Publisher | Springer, 2016 |
| ISBN | 9402408444, 9789402408447 |
| Length | 276 pages |
| Subjects | › › Medical / General Medical / History Medical / Oncology / General Medical / Pharmacy |
| Export Citation | BiBTeX EndNote RefMan |