Advances in Immunology, Volume 84

Front Cover
Elsevier, Aug 11, 2004 - Medical - 296 pages
Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research. - Interactions between NK Cells and B Lymphocytes - Multitasking of helix-loop-helix proteins in lymphopoiesis - The pathogenesis of Diabetes in the NOD Mouse
 

Selected pages

Contents

Chapter 1 Interactions Between NK Cells and B Lymphocytes
1
Chapter 2 Multitasking of HelixLoopHelix Proteins in Lymphopoiesis
43
Chapter 3 Customized Antigens for Desensitizing Allergic Patients
79
Chapter 4 Immune Response Against Dying Tumor Cells
131
Chapter 5 HMGB1 in the Immunology of Sepsis Not Septic Shock and Arthritis
181
ReceptorControlled Checkpoints in TCell Development
201
Chapter 7 The Pathogenesis of Diabetes in the NOD Mouse
239
Index
265
Contents of Recent Volumes
277
Color Plate Section
282
Copyright

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Advances in Immunology, Volume 84
Frederick W. Alt
No preview available - 2004

Common terms and phrases

Acad adjuvant allergen Allergy Allergy Clin antigen antitumor APCs apoptosis apoptotic apoptotic cells Biol birch pollen Boehmer Cancer caspases CD4+ CD8+ T cells cell death cellular clinical clones cytokine cytotoxic dendritic cells diabetes differentiation disease DNA vaccines E-protein effect effector encoding enhance epitopes exosomes function genetic helix-loop-helix proteins HMGB1 human hypoallergenic IFN-g IgE binding IgG2a immune response immune system immunogenicity immunoglobulin Immunol immunotherapy induce infection inhibition interaction islet kinase Kroemer ligands lineage lymphocytes lymphoid macrophages maturation mechanisms mediated MHC class MHC molecules murine mutation Natl natural killer cells necrosis negative selection NK cells NOD mice NOD mouse pathway patients peptides pollen allergen positive selection pre-TCR Proc production proliferation receptor recombinant regulation role sepsis septic shock severe sepsis signaling specific stimulation T-cell T-cell development target thymic thymocytes thymus transcription factors transgenic transgenic mice trigger tumor cells vitro vivo Wang

About the author (2004)

Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.

Bibliographic information

TitleAdvances in Immunology, Volume 84
Advances in Immunology
AuthorFrederick W. Alt
PublisherElsevier, 2004
ISBN0080490344, 9780080490342
Length296 pages
Subjects › 

Medical / Immunology
  
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