The Basic Science of OncologyIan Tannock This concise text examines cancer causation and biology as well as the biology underlying cancer treatment. Thoroughly updated and reorganized with five new chapters, the Fourth Edition emphasizes new development in molecular biology, hormone therapy, and the pharmacology of anti-cancer drugs. Features updated coverage of the basic science of radiotherapy and experimental radiation in addition to expansive coverage of new drugs developments. |
Contents
Chemical and Radiation Carcinogenesis | 25 |
Methods of Molecular Analysis | 49 |
Genomic Stability and DNA Repair | 77 |
Copyright | |
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activity agents angiogenesis antibody anticancer drugs antigen apoptosis assay associated binding Biol breast cancer cancer cells Cancer Res carcinogens carcinoma cell cycle cell death cell lines cellular Chap chemotherapy chromosome cisplatin Clin clinical trials colorectal complex cyclin cytokines cytotoxic dendritic cells detected disease DNA damage DNA repair domain dose effects enzyme estrogen exposure expression extracellular Figure fraction function gene genetic genome growth factor hormone human tumors immune increased induced infection inhibit inhibitors interaction irradiation lead leukemia levels ligand lung lymphocytes lymphoma malignant mechanisms membrane metastasis metastatic mice molecular molecules mutations normal tissues oncogene Oncol pathways patients peptide percent phase phosphorylation prostate cancer protein radiation radiotherapy receptor regulation response risk role sequence signaling specific stem cells studies survival curve T-cell target telomerase telomere therapeutic therapy tion toxicity transcription factors treatment tumor cells tumor suppressor types tyrosine kinase VEGF viral virus vivo