NF-kB in Health and Disease

Front Cover
Michael Karin
Springer Science & Business Media, Apr 26, 2011 - Medical - 268 pages
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Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology—from immunity and inflammation to apoptosis, cell survival, growth, and proliferation
 

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Contents

107 NF kappa BRel Proteins and the Humoral Immune Responses of Drosophila melanogaster
25
106 Specialized Chromatin Patterns in the Control of Inflammatory Gene Expression
61
98 IKK Regulation and Human Genetics
73
101 Control of NF kappa B Activity by Proteolysis
97
102 NF kappa B and Innate Immunity
115
103 NF kappa B and Mucosal Homeostasis
144
97 IKK and NF kappa BMediated Functions in Carcinogenesis
159
100 Macrophages and NF kappa B in Cancer
171
The Plot Thickens
185
108 NF kappa B as a Target for Oncogenic Viruses
197
105 Inhibition of NF kappa B Signaling as a Strategy in Disease Therapy
245
Index
265
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