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acid activity acute adducts administration aflatoxin agents animals assay assessment benzo(a)pyrene bioaccumulation BIOCHEM BIOL blood brain cadmium calcium carcinogenicity cell lines Cent Chem chemical chloride chronic cisplatin Coll compounds concentrations copper culture cyclophosphamide cytochrome cytotoxicity decreased detection diet dietary dose drug En;en Enjen ENVIRON environmental enzymes erythrocytes ethanol evaluation excretion fish genotoxicity glutathlone hamsters Health hepatic hepatocytes Hosp human increased induced inhibition injection Inst Japan kidney levels lipid liver lung cancer male mercury metabolism metabolites metals methyl mg/kg mice micronuclei microsomes mutagenicity MUTAT mycotoxins Natl neurotoxicity occupational exposure ondansetron oral organochlorine oxide P.O. Box patients pesticides Pharm Pharmacol plasma poisoning pollution protein rabbits rats renal reports risk samples selenium serum side effects significantly sodium species tion tissue toxicity toxicity testing TOXICOL toxin TRACE ELEM treatment tumors Univ urine venom vitro vivo xenobiotics zinc