Advances in Optical Biopsy and Optical MammographyRobert R. Alfano Proceedings of a conference by the New York Academy of Sciences held in 1997. The papers explore optical biopsy and optical mammography - new techniques that allow investigators to determine whether a tissue is cancerous without using invasive techniques. The text offers an analysis of the spectrum light emitted from optically excited tissue which allows investigators to detect physical and chemical changes in tissue and determine whether the tissue is normal, benign or cancerous. |
Contents
TimeResolved and Nonlinear Optical Imaging for Medical Applications | 14 |
NearInfrared Images Using Continuous PhaseModulated and Pulsed | 29 |
Fluorescence Lifetime Spectroscopic Imaging with Measurements | 46 |
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absorber absorption coefficient adenoma amplitude autofluorescence backscattering Barrett's esophagus Beer-Lambert law biological biological tissues breast cancer breast tissues cells cellular classical path clinical collagen concentration confocal microscope cytokeratin detection detector developed diffusion dysplasia emission excitation wavelength fiber FIGURE fluorescence intensity fluorescence signal fluorophores function gate group path histological human breast inflammatory ink additive Intralipid J. G. FUJIMOTO laser laser-induced fluorescence layer lesions Lett light lobular malignant mammography measurements metabolism method modulation mucosa NADH normal bladder mucosa normal mucosa normal tissue OCT imaging optical biopsy optical coherence tomography optical diagnosis optical imaging optical properties optode optode separations path integral pathology patients phantom phase photon migration photon path polarization pulse R. R. ALFANO resolution sample scanning spectra spectroscopy spectrum surface techniques time-resolved tumor turbid media two-photon excitation two-photon excitation microscopy visible bladder tumor vivo human skin wavelength