Epigenetics, Environment, and Genes

Front Cover
Sun Woo Kang
CRC Press, Apr 16, 2013 - Science - 334 pages
This title includes a number of Open Access chapters.Epigenetics refers to DNA and chromatin modifications that play an important role in the regulation of various genomic functions. This important book reviews human and cellular data that underline paradoxical findings with respect to the contribution of heredity and environment to phenotype. The
 

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Contents

CORRELATING CpG ISLANDS MOTIFS AND SEQUENCE VARIANTS
21
DNA METHYLATION
39
PROMOTER HYPERMETHYLATION
41
GENOMEWIDE MAPPING
71
HISTONE MODIFICATIONS
111
GENE SILENCING
113
HISTONE H1 PHOSPHORYLATION
155
POSTTRANSLATIONAL MODIFICATIONS
191
CHROMATIN MODIFICATIONS
203
CHROMATIN SIGNATURE
205
BIVALENT CHROMATIN MODIFICATION
239
THE ROLE OF ENVIRONMENT DURING EVOLUTION
263
ADAPTIVE DIVERGENCE
265
AUTHOR NOTES
289
Back Cover
296
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About the author (2013)

Sun Woo Kang, MD, PhD, is Assistant Professor in the Division of Nephrology of the Department of Internal Medicine a the College of Medicine at Inje University, Korea. Dr. Kang earned his PhD and MD degrees at the Kyung Hee University Medical School in Seoul, Korea. He received a National Kidney Foundation Fellowship at the University of California at San Diego (Division of Nephrology, Department of Medicine) in 2009-2010. He has received several research grants and has several years of clinical trial experience. He is also a published author and presenter at professional meetings.

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