Neuromuscular Blocking Agents: Past, Present, and Future : Proceedings of the David Savage Memorial Interface Symposium, London, 1-2 June 1990 |
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Contents
Introduction | 1 |
Neuromuscular blocking agents of the future | 15 |
clinical usefulness of | 36 |
Copyright | |
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acetylcholine action activity administration adverse Anaesth anaesthesia anaesthetic Anesthesiology arterial atracurium blockade blood cardiovascular caused changes clinical compared compounds concentration critically curare decrease depolarizing determined dose dose-response doxacurium duration duration of action edrophonium effects et al experiments failure function given half-life heart rate histamine release humans important increase induction infusion initial injection intubation isolated levels maintenance doses mean measured mechanism metabolite mg/kg mivacurium molecules monitoring muscle relaxants neostigmine nerve neuromuscular blocking agents neuromuscular blocking drugs nondepolarizing normal observed occur onset pancuronium paralysis patients pharmacokinetics pharmacology pipecuronium plasma possible potential practice present pressure produce prolonged rapid ratio reactions received receptor recovery relatively renal reports residual respectively response reversal showed shown side effects significant similar spontaneous stimulation surgery suxamethonium Table tests tion tubocurarine twitch height vecuronium µg/kg