Chromosomal Heterogeneity and Tumor-producing Capacity of a Mouse Sarcoma: Isolation of Five Single Cell Clones in Vitro |
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Contents
ISOLATION OF CLONES | 12 |
TUMORPRODUCING CAPACITY OF CELL LINES | 40 |
CHROMOSOME STUDIES | 75 |
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Common terms and phrases
aneuploid antigen approximately arm ratio ascites tumors atypical chromosomes Average Tumor Diameter behavior bi-armed chromosomes Cancer cell line cells per colony centromere chromo chromosome arms chromosome constitution chromosome number chromosomes of Clone clonal lines CLONE I CLONE Clone III Clone IV Clone V tumors colchicine counts culture fluid cytological derived described Diameter in Milimeters differences in growth diploid experiment fibroblasts Figure Foley S-180 cells frequency genetic Growth curves growth pattern growth potential growth rate Hauschka host hypertetraploid ICR mice incubation indicates inoculation large numbers Levan mean number metacentric metaphase mice morphological mouse tumor mutants near-tetraploid number of cells number of chromosome observed obtained octoploid parent cells parent line percentage petri dish Phase contrast Photomicrograph ploidy polyploid progressive growth progressive tumors sarcoma serum single cell small numbers solid tumor stemline studies Table tetraploid tissue culture total number transplantable tumors trypsinization tube tumor growth tumor regression tumor-producing capacities variation vitro vivo