Use of Laboratory Animals in Biomedical and Behavioral Research
National Academies, Jan 1, 1988 - Medical - 102 pages
The use of animals in scientific research has been a controversial issue for over a hundred years. Research with animals has saved human lives, lessened human suffering, and advanced scientific understanding, yet that same research can cause pain and distress for the animals involved and may result in their death. It is hardly surprising that animal experimentation raises complex questions and generates strong emotions. The recognition that animals are essential in scientific research is critical in making decisions about their use, but these decisions are also made in the broad context of social and ethical values. This report addresses these issues and examines how and why animals are used in research and how society oversees that research. Specifically discussed in this volume are animal use patterns, benefits from the use of animals, alternative research methods, and the use of pound animals. The appendixes include the 1896 statement on this subject by the National Academy of Sciences. Commission and committee members are listed in this report. (CW)
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Academy of Sciences agencies alternative methods anesthetized animal experimentation animal experiments animal facilities animal research Animal Resources Animal Rights Animal Welfare Act animals in biomedical animals in research APHIS behavioral research biological biomedical and behavioral biomedical research carcinogenicity cells conducted cost Department of Agriculture dogs and cats Draize test effects example federal freemartin funds genetic Guide Health Research Extension IACUC imals increased Institutes of Health investigators involving animals Laboratory Animal Resources laboratory animals mammals medical research Medicine models monkeys myasthenia gravis National Academy National Institutes National Research Council nonhuman primates nonmammalian number of animals Office of Technology organizations pain percent PHS policy pound animals pounds and shelters primates procedures rabbits rats and mice reduce the number regulations regulatory research animals Research Extension Act rodents scientific scientists society species studies Technology Assessment 1986 toxicity transplantation treatment U.S. Department University vaccines vertebrates veterinarian virus