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acceleration adaptation adenine algae algal altitude amino acids animals astronaut atmosphere bacteria behavioral bioregenerative biosatellite bioscience brain carbon dioxide carbonaceous chondrites cells changes chemical chimpanzee closed ecological system compounds concentration culture dark areas detected diet Earth organisms effects of weightlessness efficiency electrolysis energy environmental enzyme Exobiology experimental experiments exploration exposure extraterrestrial factors function gas exchange genetic gravity growth hibernation human hydrogen Hydrogenomonas hypothermia increase investigations laboratory life-support systems liters Mars Martian environment material ments Mercury messenger RNA metabolic meteorites mice molecular molecules monkeys NASA nitrogen normal nutrient nutritional observed oxygen percent periods photosynthetic physiological planetary plants possible pressure primitive problem produced Project Mercury protein proteinoid radiation rats reduced rotation Science simulated Martian space environment space flight spacecraft spores sterilization storage studies surface survival synthesis temperature terrestrial tion tissue urine vestibular weightlessness