This book reviews the most recent developments in the patho-physiology and therapy of ventilatory failure. It containscontributions by twenty-five internationally recognized aut-horities on respiratory muscle function and investigatorsactively contributing to our knowledge of the cause, diagno-sis and therapy of ventilatory failure. Of particular inter-estare the descriptions of new modalities of partial andcomplete ventilatory assistance as well as new knowledge re-garding ventilatory control and fatigue during stressfulbreathing. The reader will find here a state-of-the-art re-view of the latest research and practical applications inthis most critical area of intensive care medicine.
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Extrapulmonary and Intrapulmonary Determinants
Control of Ventilation and Response to Loading
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abdominal acute respiratory failure airflow airway occlusion airway pressure alveolar pressure alveolar ventilation Appl Physiol arterial assess barotrauma blood gas breathing pattern C0PD patients changes chest wall chronic obstructive pulmonary Clin clinical contractile CPAP decrease diaphragm dynamic hyperinflation dyspnea effect elastic electromyogram end-expiratory flail chest frequency gas exchange Grassino hypercapnia hyperinflation hypoventilation hypoxemia increase inspiration inspiratory effort inspiratory flow inspiratory pressure kyphoscoliosis load lung volume Macklem PT maneuver maximal measured mechanical ventilation metabolic Milic-Emili neural neuromuscular obstructive pulmonary disease occlusion pressure output oxygen patients with C0PD patients with chronic PEEP PEEPi phrenic nerve PImax Pmus positive pressure pressure support pressure ventilation reduced resistance respiratory muscle respiratory muscle fatigue respiratory muscle strength respiratory system response Rev Respir rib cage Roussos spontaneous breathing stimulation technique tension theophylline Thorax tidal volume tion transdiaphragmatic pressure ventilatory failure weaning from mechanical