Acute Renal Failure: A Companion to Brenner and Rector's The KidneyThe most common reason for a renal consult in a hospitalized patient is acute renal failure (ARF). This new companion book to Brenner and Rector's The Kidney provides the reader with the complete information necessary to understand, diagnose, and treat this serious and challenging condition. The first part of the book describes recent progress in the understanding of the pathophysiology of ARF, explaining the tremendous strides in the molecular and cellular aspects of cell injury and recovery. The remainder (and majority) of the text emphasizes the clinical spectrum and management of the different disease processes causing ARF. In these chapters, ARF is discussed in terms of its many associated disease processes such as pigment nephropathy, burns, infectious disease, and gastrointestinal and liver disease. This format allows for rapid referral and an in-depth understanding of all clinical aspects of ARF, including its most important aspect of management: to prevent the disease from becoming chronic, ultimately leading to dialysis and then transplantation. |
Common terms and phrases
acid acidosis actin activity acute renal failure adhesion allograft apoptosis apoptotic ARF patients associated ATP depletion binding Biol Chem biopsy blood burn burn injury cadherin calcium caspases Cell Biol cell death cellular chaperones chronic Clin Invest clinical complex cortical creatinine cyclosporine cytoskeleton decrease dialysis drugs dysfunction effects endothelial enzyme epithelial cells expression fluid gene glomerular growth factor heat shock heme hemoglobin hemoglobinuria hemolysis HSPs hyperkalemia hyponatremia increased induced infection inhibition inhibitors interstitial intracellular ischemia ischemic injury kidney Kidney Int kinase levels liver mechanisms mediated membrane metabolism mRNA muscle nephritis Nephron nephrotoxicity nitric oxide normal obstruction occur pathways Physiol plasma potassium prerenal proximal tubule rat kidney receptor regulation renal artery renal function renal injury renal ischemia reperfusion response result rhabdomyolysis role sepsis serum signaling Soc Nephrol sodium stress proteins studies syndrome therapy tight junction tion tissue toxic treatment tubular cells urinary urine vascular vivo