Nickel and Its Surprising Impact in Nature, Volume 2

Front Cover
Astrid Sigel, Helmut Sigel, Roland K. O. Sigel
John Wiley & Sons, Mar 13, 2007 - Science - 736 pages
Helmut Sigel, Astrid Sigel and Roland K.O. Sigel, in close cooperation with John Wiley & Sons, launch a new Series “Metal Ions in Life Sciences”. The philosophy of the Series is based on the one successfully applied to a previous series published by another publisher, but the move from “biological systems” to “life sciences” will open the aims and scope and allow for the publication of books touching on the interface between chemistry, biology, pharmacology, biochemistry and medicine.

Volume 2 focuses on the vibrant research area concerning nickel as well as its complexes and their role in Nature. With more than 2,800 references and over 130 illustrations, it is an essential resource for scientists working in the wide range from inorganic biochemistry all the way through to medicine.

In 17 stimulating chapters, written by 47 internationally recognized experts, Nickel and Its Surprising Impact in Nature highlights critically the biogeochemistry of nickel, its role in the environment, in plants and cyanobacteria, as well as for the gastric pathogen Helicobacter pylori, for gene expression and carcinogenensis. In addition, it covers the complex-forming properties of nickel with amino acids, peptides, phosphates, nucleotides, and nucleic acids. The volume also provides sophisticated insights in the recent progress made in understanding the role of nickel in enzymes such as ureases, hydrogenases, superoxide dismutases, acireductone dioxygenases, acetyl-coenzyme A synthases, carbon monoxide dehydrogenases, methyl-coenzyme M reductases...and it reveals the chaperones of nickel metabolism.

 

Contents

1 Biogeochemistry of Nickel and Its Release into the Environment
1
2 Nickel in the Environment and Its Role in the Metabolism of Plants and Cyanobacteria
31
3 Nickel Ion Complexes of Amino Acids and Peptides
63
4 Complex Formation of NickelII and Related Metal Ions with Sugar Residues Nucleobases Phosphates Nucleotides and Nucleic Acids
109
5 Synthetic Models for the Active Sites of NickelContaining Enzymes
181
6 Urease Recent Insights on the Role of Nickel
241
7 Nickel Iron Hydrogenases
279
8 MethylCoenzyme M Reductase and Its Nickel Corphin Coenzyme F430 in Methanogenic Archaea
323
11 Biochemistry of the NickelDependent Glyoxalase I Enzymes
445
12 Nickel in Acireductone Dioxygenase
473
13 The NickelRegulated Peptidyl Prolyl cistrans Isomerase SlyD
501
14 Chaperones of Nickel Metabolism
519
15 The Role of Nickel in Environmental Adaptation of the Gastric Pathogen Helicobacter pylori
545
16 NickelDependent Gene Expression
581
17 Nickel Toxicity and Carcinogenesis
619
Subject Index
661

9 AcetylCoenzyme A Synthases and NickelContaining Carbon Monoxide Dehydrogenases
357
10 Nickel Superoxide Dismutase
417

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About the author (2007)

Astrid Sigel has studied languages and was an editor of the Metal Ions in Biological Systems series (until Volume 44) and also of the Handbooks on Toxicity of Inorganic Compounds (1988), on Metals in Clinical and Analytical Chemistry (1994; both with H.G. Seiler), and on Metalloproteins (2001; with Ivano Bertini) (Dekker, New York).

Helmut Sigel is Emeritus Professor (2003) of Inorganic Chemistry at the University of Basel, Switzerland, and a previous editor of the MIBS series until Volume 44. He serves on various editorial and advisory boards, published over 300 articles on metal ion complexes of nucleotides, coenzymes, and other ligands of biological relevance, and lectured worldwide. He was named Protagonist in Chemistry (2002) by ICA (issue 339); among further honors are the P. Ray Award (Indian Chemical Society, of which he is also an Honorary Fellow), the Werner Award (Swiss Chemical Society), a Doctor of Science honoris causa degree (Kalyani University, India), appointments as Visiting Professor (e.g., Austria, China, UK) and Endowed Lectureships.

Roland K.O. Sigel is Assistant Professor (2003) of Inorganic Chemistry at the University of Zürich, Switzerland, endowed with a Förderungsprofessur of the Swiss National Science Foundation. He received his doctoral degree summa cum laude (1999) from the University of Dortmund, Germany, working with Bernhard Lippert; thereafter he spent nearly three years at Columbia University, New York, USA, in the group of Anna Marie Pyle (now Yale University); during the six years abroad he received several fellowships from various sources. His research focuses on the structural and catalytic role of metal ions in ribozymes, especially group II introns, and on related topics. He was also an editor of Volumes 43 and 44 of the MIBS series.

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