Accurate Results in the Clinical Laboratory: A Guide to Error Detection and CorrectionThis practical, easy-to-use guide, named to Doody’s Core Titles 2013, addresses interference issues in all laboratory tests, including patient epigenetics, process of specimen collection, enzymes, biomarkers. Clinicians and laboratory scientists can therefore rely on one reference which speaks to both their needs of accurate specimen analysis and optimal patient care. Erroneous hospital and pathology laboratory results can be confusing and problematic, especially in acute care situations. While some factors creating interference, can be identified in the laboratory, detecting many others is often dependent on clinical details unavailable to the laboratory scientists or pathologists. Therefore, clinicians must become proficient in identifying such erroneous reports, and working with pathologists and laboratory scientists so that they can understand the source of such interferences, correct the results, and then decide what course of action must be followed for proper patient management.
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Contents
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4 Sample Processing and Specimen Misidentification Issues | 35 |
5 Hemolysis Lipemia and High Bilirubin | 53 |
6 Immunoassay Design and Mechanisms of Interferences | 63 |
7 Effect of Herbal Remedies on Clinical Laboratory Tests | 75 |
8 Challenges in Routine Clinical Chemistry Testing | 93 |
13 Issues of Interferences in Therapeutic Drug Monitoring | 195 |
14 Limitations of Drugs of Abuse Testing | 213 |
15 Challenges in Confirmation Testing for Drugs of Abuse | 233 |
16 Alcohol Determination Using Automated Analyzers | 247 |
17 PreAnalytical Issues and Interferences in Transfusion Medicine Tests | 273 |
18 Issues with Immunology and Serology Testing | 295 |
19 Sources of Errors in Hematology and Coagulation Testing | 305 |
20 Challenges in Clinical Microbiology Testing | 315 |
9 Challenges in Routine Clinical Chemistry Analysis | 131 |
10 Sources of Inaccuracy in Biochemical Genetics Testing | 149 |
11 Challenges in Endocrinology Testing | 155 |
12 Pitfalls in Tumor Markers Testing | 177 |