Stem Cells

Front Cover
C. Potten
Elsevier, Oct 9, 1996 - Science - 474 pages
Stem cells are relatively undifferentiated cells which are the permanent lineage ancestor cells of tissues. Newly developed molecular biological techniques and probes have made possible dramatic advances in our ability to study the lineage development of stem cells. A major impetus to develop these techniques has been to identify specific stem cells for gene therapy purposes. The role that stem cells play in the development of cancer is also an important area. This book provides up-to-date reviews on a wide variety of stem cell systems by world experts. Chapters range from descriptions of the current knowledge of the biology of stem cells, to current molecular biological approaches and clinical implications. Oncologists and cell biologists will find this book of particular interest. It will also be usefule to radiobiologist, biotechnologists, and gene therapists.
  • Provides reviews of stem cell systems by world experts
  • Covers stem cell biology in plants, invertebrates, and mammals
  • Presents clinical implications of stem cell differentiation
 

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

Chapter 1 Stem cells and cellular pedigrees a conceptual introduction
1
Chapter 2 Stem cells and founder zones in plants particularly their roots
29
Chapter 3 The stem cell concept applied to shoot meristems of higher plants
59
function and potential role in therapy
75
Chapter 5 Cell progenitors in the neural crest
99
Chapter 6 Phenotypic diversity and lineage relationships in vascular endothelial cells
119
Chapter 7 Mammary stem cells in normal development and cancer
147
Chapter 8 Liver stem cells
233
Chapter 10 Stem cell repertoire in the intestine
315
Chapter 11 Keratinocyte stem cells of cornea skin and hair follicles
331
Chapter 12 Tumour stem cells
363
Chapter 13 Biology of the haemopoietic stem cell
401
Chapter 14 Growth factors and the regulation of haemopoietic stem cells
423
Chapter 15 Haemopoietic stem cells for gene therapy
447
Index
463
Color Plates Section
475

Chapter 9 Regulation of proliferation and differentiation of stem cells in the male germ line
283

Other editions - View all

Common terms and phrases

Popular passages

Page ix - Royal Postgraduate Medical School, Hammersmith Hospital, Du Cane Road, London W12 ONN.
Page viii - Department of Biochemistry, University of Liverpool, PO Box 147, Liverpool, L69 3BX (UK...
Page viii - Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 4BX, UK.
Page vii - University of Southern California School of Medicine, 4650 Sunset Boulevard, Los Angeles, California 90027.

Bibliographic information