Manganese in Metabolism and Enzyme Function

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Vern L. Schramm
Elsevier, Dec 2, 2012 - Science - 448 pages
Manganese in Metabolism and Enzyme Function provides an understanding of the various biological roles of the trace levels of manganese found in mammalian systems. This text discusses the nutritional aspects of manganese in mammals.
This book is organized into three sections encompassing 19 chapters. Section I discusses the effects of manganese deficiency, including abnormal pancreatic action and reduced pancreatic manganese in humans and laboratory animals. This text considers the criteria for adding manganese to infant formulas that are commercially available. Section II explores the effects of Mn(II) in protein kinases, protein phosphatases, and other enzymes. The reader is introduced to the electron paramagnetic resonance spectroscopic probes of manganese function. Other chapters discuss the extrinsic tag technique used to study the bioavailability of trace elements, such as iron and zinc. Finally, Section III examines the biophysical, biochemical, and physiological properties and uses of manganese.
Nutritionists, toxicologists, scientists, and researchers will find this book extremely useful.
 

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Contents

Enzymology and Metabolic Pathways
107
Biophysical Probes for Manganese and Its Interactions with Specific Binding Sits
311

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