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Chromosomes in Evolution
Numbers in parentheses indicate the pages on which the authors contributions begin
Quinacrine and Other
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Acad activity addition amount appear associated autosomal bands Biol cells centromere changes chromatids chromo chromosomes complex constitutive contain Cytogenetics cytoplasm deletion demonstrated determined differentiation diploid Down's syndrome early elements et al evidence example female fibers fluorescent fraction frequently function gene Genet genome giant heterochromatin homologous human hybridization increased indicate individual interphase involved isolated karyotype known lateral Lejeune length less located male mammalian material mechanism medium meiotic metaphase methods mitotic Nature London normal nuclear nucleus observed obtained occur organisms origin pairing patients patterns polytene possible present probably Proc produce protein puffs recent regions replication reported represent ring segments separation sequences Sharma short shown similar single species stage staining structure studies suggested syndrome synthesis techniques tion translocation trisomy usually