Peptidomics: Methods and Applications
The definitive guide to peptidomics- a hands-on lab reference
The first truly comprehensive book about peptidomics for protein and peptide analysis, this reference provides a detailed description of the hows and whys of peptidomics and how the techniques have evolved. With chapters contributed by leading experts, it covers naturally occurring peptides, peptidomics methods and new developments, and the peptidomics approach to biomarker discovery. Explaining both the principles and the applications, Peptidomics: Methods and Applications:
Features examples of applications in diverse fields, including pharmaceutical science, toxicity biomarkers, and neuroscience
Details the successful peptidomic analyses of biological material ranging from plants to mammals
Describes a cross section of analytical techniques, including traditional methodologies, emerging trends, and new techniques for high throughput approaches
An enlightening reference for experienced professionals, this book is sufficiently detailed to serve as a step-by-step guide for beginning researchers and an excellent resource for students taking biotechnology and proteomics courses. It is an invaluable reference for protein chemists and biochemists, professionals and researchers in drug and biopharmaceutical development, analytical and bioanalytical chemists, toxicologists, and others.
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abundant Acad Sci USA affinity amino acid amplification AMPs Anal analysis analytical antibodies antigens applications assays Biochem bioinformatics Biol Chem biological biomarkers brain briggsae C-terminal cDNA characterization chemical chromatography Clin cloning cockroach complex CP4 EPSPS cysteine cytokine database defensins degradation depletion detection digestion disease drug Electrophoresis enzymes example extract fraction fragments functional genes genome groups high throughput hormones HPLC identified Immunol insect ionization iTRAQ labeled latarcins LC-MS levels Loof MALDI MALDI-TOF marker Mass Spectrom mass spectrometry membrane methods MHC-II Mol Cell Proteomics molecular molecules MS/MS Natl Acad Sci neuropeptides novel Orbitrap peptidomics peptidomics approach polypeptides posttranslational modifications potential precursor primers Proc Natl Acad processing proteases proteins proteins and peptides proteolysis proteolytic Proteomics quantification RACE-PCR reagents residues sample selected sequence Shaw signal Soloviev soya specific spectra spider strategy structure target techniques tissue toxins tryptic venom Verhaert