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17-ketosteroids acid ACTH action activity acute administered adrenal adrenal cortex analgesic anti-inflammatory assessment blood bursa Butyl Acetate cause cent chronic claims clinical trials clinicians complications condition contra-indication cortex corticosterone corticotrophin cortisone therapy degree develop diabetes discussed dosage dose of cortisone early evidence excretion experience extremely factors fluid frequently function glands glucocorticoids Hench hormones hyaluronidase hydrocortisone improvement increase indicated inflammatory injection intra-articular joint lesion lupus erythematosus maintenance dose measure medial metabolism methods needle is inserted normal occur osteoarthritis osteoporosis pain palpated peptic ulceration pharmacological phenylbutazone pituitary polyarteritis nodosa Position The patient potassium practical prednisolone prednisone problem procaine produce protein recent reduction relapse relative remission renal reported resistance response rheumatic diseases rheumatoid arthritis risk routine seems side-effects significant sodium retention specific steroid drugs steroid therapy stress suppression suprarenal supraspinatus symptoms syndrome tendon therapeutic tion tissue toxic treated treatment usually whilst withdrawn