Antibiotics and Chemotherapy, Volume 17S. Karger, 1971 - Antibiotics |
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Page 98
... metabolism like alkylating substances azaserine in organs with vivacious metabolism causes cell damage . So after parenteral administration of 100 to 200 mg / kg in rats necroses of pancreas , liver and kidney develop within 24 h . In ...
... metabolism like alkylating substances azaserine in organs with vivacious metabolism causes cell damage . So after parenteral administration of 100 to 200 mg / kg in rats necroses of pancreas , liver and kidney develop within 24 h . In ...
Page 105
... metabolism in different places and independently of the other part . 2. By far the most frequent form of isoniazid resistance concerns ex- clusively the carboxyl hydrazine group , therefore , between all the substances which possess ...
... metabolism in different places and independently of the other part . 2. By far the most frequent form of isoniazid resistance concerns ex- clusively the carboxyl hydrazine group , therefore , between all the substances which possess ...
Page 109
... metabolism of the mycobac- teria . As a result of systematic investigations , SEYDEL and his co - workers [ 55 ] believe they can set up the rule that inhibitory substances which possess a pyridine ring substituted in the 2- or 4 ...
... metabolism of the mycobac- teria . As a result of systematic investigations , SEYDEL and his co - workers [ 55 ] believe they can set up the rule that inhibitory substances which possess a pyridine ring substituted in the 2- or 4 ...
Contents
Streptomycin as an Inhibitor of Protein Biosynthesis | 29 |
The Macrolide Group of Antibiotics Mode of Action | 52 |
The Interaction of Actinomycin with | 67 |
Copyright | |
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Common terms and phrases
30S ribosomal 30S subunit 50S ribosomal subunit Acad Acta actinomycin action of Sm action of streptomycin alanine amino acids antibacterial antibiotic assay azaserine Bact bacteria bactericidal base pair binding of aminoacyl-tRNA binding of tetracycline Biochem Biol biophys carbomycin cell wall cell-free Chem chemical Chemother chromophore complex concentration culture cycloserine deoxyribonucleic acid DNA synthesis doses drug effect enzyme erythromycin Escherichia coli ethambutol formation fusidic acid growth guanine hydrogen hypothesis incorporation infections inhibitory interaction isoniazid isonicotinic acid lincomycin mechanism of action messenger RNA metabolism Mg++ ion Miscoding mode of action molec molecular molecule mycin nalidixic acid novobiocin nucleic acid nucleotides observed oleandomycin penicillin peptide poly polysomes Proc protein biosynthesis protein synthesis purines puromycin pyrazinamide reaction replication resistance ribo ribonucleic acid ribosomes ristocetin sensitive specific spiramycin staphylococci strains streptomycin structure studies tetracycline to ribosomes therapy Toxic transfer RNA tRNA tuberculostatic uptake vancomycin vitro vivo Wash µg/ml