Femtosecond Technology for Technical and Medical ApplicationsJose Russo There is no doubt that the advent of immunocytochemical techniques, by enhancing our ability to detect specific cell products or markers, has opened new avenues in the understanding of human diseases, and in our ability to perform better diagnosis in surgical pathology. The rapid development of this field has resulted in thousands of publications in the literature regarding immunocytochemistry in diagnostic pathology. This explosion of knowledge makes necessary publications summarizing what are the main markers available and how they can be used in the diagnosis of tumors. The need of a more organized and structured knowledge was evident during the workshop in Immunocytochemistry of Tumor Diagnosis that took place in the City of Detroit an October 1984. This book is the result of that workshop in which 22 chapters are focusing an the main subject of differential diagnosis of tumors. Jose Russo, M.D. Editor xiii ACKNOWLEDGEMENTS I wish to thank my many associates at the Michigan Cancer Foundation for their help in the preparation of this manuscript. I give thanks to Dr. |
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Page 231
... cells . Cancer Research ( 43 ) : 1301-1305 , 1983 . 70. Horan Hand PM , Nuti M , Colcher D , and Schlom J : Definition of antigenic heterogeneity among human mammary carcinoma cell population using monoclonal antibodies to tumor ...
... cells . Cancer Research ( 43 ) : 1301-1305 , 1983 . 70. Horan Hand PM , Nuti M , Colcher D , and Schlom J : Definition of antigenic heterogeneity among human mammary carcinoma cell population using monoclonal antibodies to tumor ...
Page 254
... tumor cells comprise a small percentage of the tumor section , they show a definite trend of the tumor as a whole towards a higher state of differentiation . Their presence intermingled with the more prevalent population of undifferentiated ...
... tumor cells comprise a small percentage of the tumor section , they show a definite trend of the tumor as a whole towards a higher state of differentiation . Their presence intermingled with the more prevalent population of undifferentiated ...
Page 324
... tumor cells is most frequently associated with testicular yolk sac tumor . This tumor constitutes about 60 % of germ cell tumors encountered in infants and children . As of this writing 19 of our 20 yolk sac tumors in this age group ...
... tumor cells is most frequently associated with testicular yolk sac tumor . This tumor constitutes about 60 % of germ cell tumors encountered in infants and children . As of this writing 19 of our 20 yolk sac tumors in this age group ...
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activity adenocarcinomas analysis antigen appears associated blood breast cancer breast carcinoma carcinoma cell carcinoma cell lymphoma cell suspension cell tumors cell type cellular characterized Clin clinical common contain correlation cultured cytokeratin cytoplasmic demonstrated derived detected diagnosis differentiation disease distribution epithelial cells epithelium estrogen receptor evaluation evidence expression Figure fixed frozen sections function histologic Hodgkin's hormones human identified immunoglobulin immunohistochemical immunohistochemistry immunological immunoperoxidase immunostaining indicate intensity intermediate filament keratin laboratory lesions leukemia light localization lymph node lymphocytes malignant mammary markers mature melanoma membrane method microscopic monoclonal antibodies negative neoplastic normal observed obtained origin ovarian paraffin Pathol pathology patients pattern peripheral phenotype positive prepared present primary produce prostatic protein reaction reactivity recently receptor reported sarcoma serum shown skin specific squamous stages staining surface T-cell Table techniques tissue tumor cells usually