Heart Development, Volume 342Richard P. Harvey, Nadia Rosenthal This book examines recent studies revealing that the same genes are responsible for development of parallel features between species, and that the heart develops similarly across all species. It includes research being conducted concerning cardiac development, tissue interaction, and organ formation. The text attempts to provide a greater understanding of the underlying causes of heart failure, heart muscle diseases, congenital malformations, and other heart diseases and defects. |
Contents
Lineage | 3 |
in Amphibian Embryos | 37 |
Genetic Determination of Drosophila | 65 |
7 | 111 |
the MEF2 Family of Transcription Factors | 131 |
Richard P Harvey Christine Biben and David A Elliott | 143 |
Mechanisms of Segmentation | 159 |
Conclusions | 179 |
19 | 333 |
Heart Development | 357 |
Establishing Cardiac | 373 |
Looping Morphogenesis | 378 |
Cardiac Looping | 391 |
The Cardiac Cell Cycle | 405 |
Symmetry and Laterality | 447 |
Atrial Appendages | 453 |
13 | 209 |
by Myocardialization | 221 |
The MLC2 Paradigm for Ventricular | 255 |
References | 273 |
Cardiac Lineages | 291 |
Multiple Layers of Control | 307 |
Conduction System | 463 |
Identification of the Etiologic Genes | 473 |
Axis Malformations | 479 |
Molecular Genetics of Skeletal | 493 |
| 519 | |
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Common terms and phrases
activin activity angiogenesis arteries asymmetry atrial atrioventricular atrium avian axis bHLH binding Biol Bodmer cardiac development cardiogenesis Cell Cambridge Chen cushion cyclin defects deletion Development Cambridge developmental dHAND differentiation domain dorsal Drosophila early ectoderm eHAND embryogenesis embryos endocardial endocardium endoderm endothelial cells epiblast expression patterns formation function gastrulation gene expression Genes Dev Genet growth factor heart development heart field heart looping heart tube homeobox gene homeodomain induction interactions left ventricle left-right markers Markwald MCAT MEF2 MEF2C mesenchyme mice midline molecular Molkentin morphogenesis mouse embryos murine muscle cells mutant myocardial myocardium myogenic myosin Natl Nature London neural crest normal notochord Olson pathway phenotype precursors primitive streak progenitors protein Randomized heart receptor region regulation regulatory right ventricle role segments signaling skeletal muscle smooth muscle somite specific Srivastava stage Stainier tinman tion tissue transcription factor transgenic vascular vasculogenesis ventral ventricular vertebrate vessels visceral VSMCs Xenopus zebrafish



