Noble Metals and Biological Systems: Their Role in Medicine, Mineral Exploration, and the Environment

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CRC Press, Apr 6, 1992 - Science - 416 pages
Noble Metals and Biological Systems examines the relationship between noble metals (gold, silver, and platinum group metals) and biological systems. The book is divided into three parts.

Part 1 is concerned with the analytical chemistry of noble metals and includes a description of the latest methods of analysis.

Part 2 describes such topics as ecology and environmental science of noble metals as they pertain to biogeochemical exploration, noble metals in hair, the environmental geochemistry of palladium, microorganisms and noble metals, animals and noble metals, and a general survey of noble metals in the environment. Coverage is comprehensive and includes information regarding the use of dogs and termites as field assistants in mineral prospecting, as well as the fascinating story of the "gold bug", a microorganism that plates itself with gold.

Part 3 is devoted entirely to noble metals in the treatment of disease and includes chapters describing the use of osmium and gold for arthritis treatment, silver as a bactericide, and platinum and ruthenium as anticancer agents.

Noble Metals and Biological Systems will provide fascinating reading for applied geochemists, environmentalists, public health specialists, ecologists, microbiologists, clinical biochemists, oncologists, and specialists in rheumatic diseases.
 

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Contents

Chapter
1
Chapter
3
Chapter
5
Chapter
6
References
14
References
40
Chapter 3
47
Chapter 4
91
NOBLE METALS IN THE ENVIRONMENT
219
Chapter 9
277
Chapter 12
296
References
297
OSMIUMAND ARTHRITIS
303
Acknowledgment
319
Compounds
340
Acknowledgments
346

THE ENVIRONMENTALGEOCHEMISTRY AND BIOGEOCHEMISTRY
129
THE NOBLE METAL BIOGEOCHEMISTRY OF MICROORGANISMS
159
Chapter 7
197
References
216
PLATINUM CHEMOTHERAPY FOR CANCERTREATMENT
349
Acknowledgments
366
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Page 367 - Methods for detecting DNA damaging agents in humans: applications in cancer epidemiology and prevention.
Page 370 - EASTMAN, A. The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes. Pharmacol. Ther. 1987, 34, 155-166. 20 BRABEC, V. Chemistry and structural biology of 1,2-interstrand adducts of cisplatin, in Platinum-Based Drugs in Cancer Therapy, eds LR Kelland and NP Farrell, Humana Press, Totowa, NJ, 2000, 37-61.

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