Evolutionary Computation in Bioinformatics

Front Cover
Gary B. Fogel, David W. Corne, Gary B.. Fogel
Morgan Kaufmann, 2003 - Computers - 393 pages
"This is a fine book that clearly discusses the applications of evolutionary computation techniques to a variety of different areas. It covers most topics a bioinformatician will find interesting."


--Santosh Mishra, Eli Lilly
hr
Bioinformatics has never been as popular as it is today. The genomics revolution is generating so much data in such rapid succession that it has become difficult for biologists to decipher. In particular, there are many problems in biology that are too large to solve with standard methods. Researchers in evolutionary computation (EC) have turned their attention to these problems. They understand the power of EC to rapidly search very large and complex spaces and return reasonable solutions. While these researchers are increasingly interested in problems from the biological sciences, EC and its problem-solving capabilities are generally not yet understood or applied in the biology community.


This book offers a definitive resource to bridge the computer science and biology communities. Gary Fogel and David Corne, well-known representatives of these fields, introduce biology and bioinformatics to computer scientists, and evolutionary computation to biologists and computer scientists unfamiliar with these techniques. The fourteen chapters that follow are written by leading computer scientists and biologists who examine successful applications of evolutionary computation to various problems in the biological sciences.


Features

  • Describes applications of EC to bioinformatics in a wide variety of areas including DNA sequencing, protein folding, gene and protein classification, drug targeting, drug design, data mining of biological databases, and biodata visualization.
  • Offers industrial and academic researchers in computer science, biology, and bioinformatics an important resource for applying evolutionary computation.
  • Includes a detailed appendix of biological data resources.
 

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

III
1
IV
3
VI
5
VII
10
VIII
11
IX
12
X
15
XI
16
CXVIII
197
CXIX
198
CXX
202
CXXI
203
CXXII
204
CXXIII
211
CXXIV
215
CXXV
216

XII
17
XIII
19
XIV
20
XV
22
XVII
24
XVIII
25
XX
26
XXII
29
XXIII
32
XXIV
33
XXV
35
XXVI
39
XXVII
41
XXVIII
43
XXX
45
XXXI
46
XXXIII
47
XXXIV
49
XXXV
55
XXXVI
59
XXXVIII
60
XXXIX
61
XL
62
XLI
63
XLII
65
XLIII
69
XLV
71
XLVI
72
XLVII
73
XLVIII
79
XLIX
84
L
87
LII
88
LIII
89
LIV
91
LV
92
LVII
93
LVIII
94
LX
95
LXIII
98
LXIV
99
LXV
100
LXVI
101
LXVII
103
LXVIII
105
LXIX
113
LXX
115
LXXI
116
LXXII
118
LXXIV
122
LXXV
126
LXXVI
128
LXXVII
129
LXXIX
130
LXXX
131
LXXXII
132
LXXXIV
133
LXXXV
137
LXXXVI
139
LXXXVIII
141
LXXXIX
142
XCI
145
XCV
146
XCVI
150
XCVII
151
XCVIII
155
XCIX
156
C
163
CI
164
CII
166
CIII
167
CIV
168
CV
171
CVI
175
CVII
177
CVIII
180
CIX
181
CX
182
CXI
183
CXII
188
CXIII
191
CXV
191
CXVI
193
CXVII
195
CXXVI
217
CXXVII
220
CXXVIII
222
CXXIX
223
CXXX
225
CXXXI
227
CXXXIV
228
CXXXV
234
CXXXVI
235
CXXXVII
237
CXXXVIII
239
CXL
241
CXLI
242
CXLII
243
CXLIII
244
CXLIV
246
CXLV
247
CXLVI
248
CXLVIII
249
CXLIX
251
CLII
252
CLIII
254
CLIV
255
CLVI
256
CLVII
258
CLVIII
259
CLIX
260
CLX
264
CLXI
268
CLXII
271
CLXIII
272
CLXIV
275
CLXVII
277
CLXVIII
278
CLXIX
280
CLXX
282
CLXXI
283
CLXXII
289
CLXXIII
291
CLXXIV
293
CLXXVII
295
CLXXVIII
297
CLXXIX
298
CLXXX
300
CLXXXI
301
CLXXXII
302
CLXXXIII
303
CLXXXIV
304
CLXXXV
305
CLXXXVII
306
CLXXXIX
308
CXC
311
CXCI
313
CXCIV
315
CXCV
317
CXCVII
318
CXCVIII
319
CXCIX
320
CCI
321
CCII
322
CCIII
323
CCIV
324
CCV
325
CCVI
326
CCVII
327
CCIX
330
CCX
337
CCXI
338
CCXII
342
CCXIII
343
CCXIV
346
CCXV
348
CCXVI
349
CCXVII
351
CCXVIII
354
CCXIX
355
CCXX
356
CCXXI
358
CCXXII
363
CCXXIII
364
CCXXIV
365
CCXXV
367
CCXXVIII
369
Copyright

Other editions - View all

Common terms and phrases

About the author (2003)

Gary B. Fogel is a senior staff scientist at Natural Selection, Inc., in La Jolla, California.His research interests include the application of evolutionary computationto problems in the biomedical sciences and evolutionary biology. He received aB.A. in biology from the University of California, Santa Cruz, in 1991 and a Ph.D.in biology from the University of California, Los Angeles, in 1998 with a focus onevolutionary biology. While at UCLA, Dr. Fogel was a fellow of the Center for theStudy of Evolution and the Origin of Life and earned several teaching and researchawards. He is a current member of the International Society for the Studyof the Origin of Life, the Society for the Study of Evolution, IEEE, Sigma Xi, andthe Evolutionary Programming Society. He currently serves as an associate editorfor IEEE Transactions on Evolutionary Computation and BioSystems and was a technicalco-chair for the recent 2000 Congress on Evolutionary Computation. He is alsoa senior staff scientist at the Center for Excellence in Evolutionary Computation,a nonprofit organization that promotes scientific research and development ofevolutionary algorithms.

David W. Corne is a reader in evolutionary computation (EC) at the University of Reading. His early research on evolutionary timetabling (with Peter Ross) resultedin the first freely available and successful EC-based general timetabling programfor educational and other institutions. His later EC work has been in suchareas as DNA pattern mining, promoter modeling, phylogeny, scheduling, layoutdesign, telecommunications, data mining, algorithm comparison issues, and multiobjectiveoptimization. Recent funded work (with Douglas Kell) applies EC directlyto the in vivo optimization of proteins. He is an associate editor of the IEEETransactions on Evolutionary Computation and a founding co-editor of the Journal ofScheduling. Dr. Corne is on the editorial boards of Applied Soft Computing and the InternationalJournal of Systems Science, and he serves on a host of international conferenceprogram committees. Other recent edited books include New Ideas in Optimization(with Marco Dorigo and Fred Glover), Telecommunications Optimization: Heuristic andAdaptive Techniques (with Martin Oates and George Smith), and Creative EvolutionarySystems (with Peter Bentley). He is also a director of Evosolve (United Kingdomregistered charity number 1086384, with Jeanne Lynch-Aird, Paul Marrow, GlenysOates, and Martin Oates), a nonprofit organization that promotes the use of advancedcomputation technologies to enhance the quality of life.

Bibliographic information